Motor Evoked Potential in the Affected Upper Limb Predicts the Potential of Motor Recovery in Subacute Stroke Patients

NCT ID: NCT03243318

Last Updated: 2022-05-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-11

Study Completion Date

2021-11-30

Brief Summary

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Stroke is the third common cause of adult disability in dveloped countries. Early identification of the potential for motor recovery is important to avoid 'learned disuse' and to initiate appropriate therapy with achievable goals. The current cohort study focuses on those patients with SAFE \<8 and using motor evoked potentials (MEPs) to improve on prognostication of upper limb motor recovery among subacute stroke patients in a local stroke population.

Detailed Description

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Conditions

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Stroke, Subacute

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Presence of motor evoked potentials

Those patients with Shoulder Abduction and Finger Extension (SAFE) score \<8/10 with the presence of motor evoked potentials elicited by TMS over the ipsilesional motor cortex

MEPs induced by TMS

Intervention Type DIAGNOSTIC_TEST

Using TMS induced MEPs over motor cortex of the affected side to predict motor recovery potentials

absence of motor evoked potentials

Those patients with Shoulder Abduction and Finger Extension (SAFE) score \<8/10 with the absence of motor evoked potentials elicited by TMS over the ipsilesional motor cortex

MEPs induced by TMS

Intervention Type DIAGNOSTIC_TEST

Using TMS induced MEPs over motor cortex of the affected side to predict motor recovery potentials

Interventions

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MEPs induced by TMS

Using TMS induced MEPs over motor cortex of the affected side to predict motor recovery potentials

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* First stroke with hemiparesis or hemiplegia with SAFE \<8

Exclusion Criteria

* contra-indication to TMS or MRI, history of seizure, pregnancy and mentally unfit to understand the consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital Authority, Hong Kong

OTHER_GOV

Sponsor Role lead

Responsible Party

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Eric Man Pun Yeung

Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Rehabilitation, Kowloon Hospital

Hong Kong, , Hong Kong

Site Status

Countries

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Hong Kong

Other Identifiers

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KHMEPsUL2017

Identifier Type: -

Identifier Source: org_study_id

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