Working Memory Training in COPD Patients: the Cogtrain-Trial

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-01

Study Completion Date

2019-07-01

Brief Summary

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General cognitive impairment is highly prevalent in chronic obstructive pulmonary disease (COPD) patients. Domain-specific cognitive impairments include deficits in domains such as cognitive flexibility, verbal memory, working memory, planning, and psychomotor speed; which in general are associated with poor health behaviours, such as infrequent exercising and poor diet. Additional cognitive training may reverse these effects. Recent evidence suggests that working memory training is linked to self-control and, indirectly, to improved lifestyle behaviour including increased physical activity. The investigators hypothesise that enhancing cognitive performance through administering specific working memory training not only improves cognitive function but that it facilitates better adherence to a more active lifestyle and a healthier diet in COPD patients.

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Detailed Description

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Conditions

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COPD Cognitive Impairment

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Working memory training

Working memory training that increases with difficulty if participants answer two subsequent questions correctly, and standardised healthy lifestyle coaching.

Group Type ACTIVE_COMPARATOR

Working memory training

Intervention Type OTHER

The working memory intervention training programme consists of a domain-general cognitive working memory training programme. One training session will take 20 to 30 minutes, and participants will have to complete approximately 40 cognitive training sessions.

The sham treatment is the same as the intervention training however it does not increase in difficulty. Participants are presented with the same task at the same level of difficulty over and over again. Thus a training effect is not expected.

Standardised healthy lifestyle coaching

Intervention Type BEHAVIORAL

Participants will receive standardised healthy living coaching focusing on healthy diet and daily physical activity.

Sham working memory training

Working memory training that does not increase in difficulty, and standardised healthy lifestyle coaching.

Group Type SHAM_COMPARATOR

Working memory training

Intervention Type OTHER

The working memory intervention training programme consists of a domain-general cognitive working memory training programme. One training session will take 20 to 30 minutes, and participants will have to complete approximately 40 cognitive training sessions.

The sham treatment is the same as the intervention training however it does not increase in difficulty. Participants are presented with the same task at the same level of difficulty over and over again. Thus a training effect is not expected.

Standardised healthy lifestyle coaching

Intervention Type BEHAVIORAL

Participants will receive standardised healthy living coaching focusing on healthy diet and daily physical activity.

Interventions

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Working memory training

The working memory intervention training programme consists of a domain-general cognitive working memory training programme. One training session will take 20 to 30 minutes, and participants will have to complete approximately 40 cognitive training sessions.

The sham treatment is the same as the intervention training however it does not increase in difficulty. Participants are presented with the same task at the same level of difficulty over and over again. Thus a training effect is not expected.

Intervention Type OTHER

Standardised healthy lifestyle coaching

Participants will receive standardised healthy living coaching focusing on healthy diet and daily physical activity.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* primary diagnosis of COPD based on the Global Initiative for Chronic obstructive Lung Disease (GOLD) guidelines
* Patients also need to provide written informed consent
* Be motivated as evaluated by the self-determination questionnaire

Exclusion Criteria

* Disease and or disability limiting the ability to undergo a neuropsychological testing battery and/or to follow a working memory training (e.g., blindness)
* Neurological disorders (e.g., Alzheimer's Disease or cerebrovascular disease)
* Insufficient mastery of the Dutch language
* Individuals who during the study period are or will be participating in a PR programme

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No