Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
6 participants
INTERVENTIONAL
2012-08-31
2014-09-30
Brief Summary
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The hypotheses are:
1. post-training cognitive performance will be superior to pre-training cognitive performance
2. post-training depressive symptomatology will be less severe as compared with pre-training clinical severity and
3. AUT group will show better post-training cognitive performance and improved mood symptoms when compared with the WAT group.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Alternative Uses Training
In this task, subjects are asked to produce atypical and alternative uses for common daily objects.
Cognitive training
20 minutes/day for 5 sequential working days
Word Association Training
In this task, subjects are asked to generate the first word that comes to their mind, and thus, encourages more general and spontaneous divergent thinking.
Cognitive training
20 minutes/day for 5 sequential working days
Interventions
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Cognitive training
20 minutes/day for 5 sequential working days
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Age \>=55
* Proficiency in English
* Current depressive episode and meet criteria for DSM-IV major depressive disorder
* Hamilton Depression Rating Scale score \>=15
* Able to give informed consent
* Stable medication dosages during the training period
Exclusion Criteria
* Mini-Mental State Examination score of \<26
* Diagnosis of dementia
* Neurological and medical conditions known to affect cognition (e.g., stroke, head injury, previous chemotherapy for cancer)
* Unstable medical illnesses requiring active treatment
* Vision or hearing impairment affecting ability to participate in training
55 Years
ALL
No
Sponsors
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Baycrest
OTHER
Rotman Research Institute at Baycrest
OTHER
Responsible Party
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Linda Mah, MD
Clinician Scientist
Principal Investigators
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Linda Mah, MD, M.H.Sc.
Role: PRINCIPAL_INVESTIGATOR
Rotman Research Institute at Baycrest
Locations
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Rotman Research Institute at Baycrest
Toronto, Ontario, Canada
Countries
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Other Identifiers
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12-28
Identifier Type: -
Identifier Source: org_study_id
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