Measurement of Anterior Chamber Cell Grading Using Ocular Coherence Tomography

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

6 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-09-30

Study Completion Date

2018-04-30

Brief Summary

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Optical Coherence Tomography (OCT) is routinely used in ophthalmic clinical practice. It uses infrared light to image patient's eyes. Some patients, such as those with an inflammatory disease called uveitis or those who have just undergone cataract surgery, have intraocular inflammation. This intraocular inflammation commonly manifests as cells that can be seen on routine microscopic clinical examination. However, the only currently available method to quantify this intraocular inflammation is by manually counting on the microscopic clinical examination. The investigators plan to use the OCT machine to image patient's eyes. The investigators will then use the images obtained from the OCT to objectively quantify the degree of intraocular inflammation.

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Detailed Description

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Conditions

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Uveitis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Uveitis and Cataract Imaging Group

Subjects will undergo up to three optical coherence tomography scans.

Group Type EXPERIMENTAL

Optical Coherence Tomography (OCT)

Intervention Type DEVICE

The OCT scan is a brief, non-contact scan of the back of the eye using infrared light. Subjects will see a light and be asked to look forwards while the scan is completed.

Control

Control subjects will undergo a brief, non-contact eye exam and then undergo up to three optical coherence tomography scans.

Group Type EXPERIMENTAL

Optical Coherence Tomography (OCT)

Intervention Type DEVICE

The OCT scan is a brief, non-contact scan of the back of the eye using infrared light. Subjects will see a light and be asked to look forwards while the scan is completed.

Eye Exam

Intervention Type OTHER

This is a brief, non-contact ocular exam.

Interventions

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Optical Coherence Tomography (OCT)

The OCT scan is a brief, non-contact scan of the back of the eye using infrared light. Subjects will see a light and be asked to look forwards while the scan is completed.

Intervention Type DEVICE

Eye Exam

This is a brief, non-contact ocular exam.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age over 18 years old
* Intervention Arm:

* Active anterior chamber inflammation in at least one eye as diagnosed by clinical exam
* One of the following: 1) diagnosis of uveitis OR 2) undergone cataract extraction surgery within the previous 30 days
* Control Arm:

* No active intraocular inflammation based on clinical exam