A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging

NCT ID: NCT00556114

Last Updated: 2022-10-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

23 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-01-31

Study Completion Date

2013-07-31

Brief Summary

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Growing evidence shows that altered blood flow plays a major role in many vision-threatening diseases including glaucoma, diabetic retinopathy, age-related macular degeneration, Central Retinal Vein Occlusion, and Branch Retinal Vein Occlusion. Optical coherence tomography, an established imaging technique use for eye exam in clinical ophthalmology, provides high-resolution cross sectional images of the retina and has increased our ability to understand many eye diseases.

Detailed Description

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Optical Coherence Tomography is a non-invasive technique use a broadband light source to illuminate the area of study with light in the near infrared spectrum, then obtains static images of tissue structure from interference signals of the back-reflected light.

Optical Coherence Tomography a non-contact, non-invasive means of documenting both tissue structure and blood flow changes in ocular disease and can provide high resolution cross-sectional images of tissue structure, direct visualization of blood flow in blood vessels of the eye.

Conditions

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Glaucoma Diabetic Retinopathy Age-Related Macular Degeneration Central Retinal Vein Occlusion Branch Retinal Vein Occlusion

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Optical Coherence Tomography

Optical Coherence Tomography

Optical Coherence Tomography

Intervention Type DEVICE

Optical Coherence Tomography

Interventions

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Optical Coherence Tomography

Optical Coherence Tomography

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult 18 years and older with normal eye, or has been diagnosed with eye disease.

Exclusion Criteria

* Less than 18 years of age.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Beckman Laser Institute University of California Irvine

OTHER

Sponsor Role collaborator

University of California, Irvine

OTHER

Sponsor Role lead

Responsible Party

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Beckman Laser Institute and Medical Center

Baruch D. Kuppermann, M.D., Ph.D.,Professor Department of Ophthalmology and Biomedical Engineering

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Baruch D Kuppermann,, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Ophthamology, University of California,Irvine

Zhongping Chen, Ph,D

Role: PRINCIPAL_INVESTIGATOR

Beckman Laser Institute University of California Irvine

Locations

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Beckman Laser Institute, University of California,Irvine

Irvine, California, United States

Site Status

Countries

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United States

Other Identifiers

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20043555

Identifier Type: -

Identifier Source: org_study_id

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