Taste Physiology in Obese Volunteers Before and After Bariatric Surgery
NCT ID: NCT02902198
Last Updated: 2025-04-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
16 participants
INTERVENTIONAL
2014-12-31
2027-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
TRIPLE
Study Groups
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Placebo preoperative
Single intragastric instillation of 200ml tap water via nasogastric tube
Placebo
Tap water 200ml
Placebo postoperative
Single intragastric instillation of 200ml tap water via nasogastric tube
Placebo
Tap water 200ml
Glucose preoperative
Single intragastric instillation of 200ml tap water with 25g glucose via nasogastric tube
Glucose
25g Glucose in 200ml tap water
Glucose postoperative
Single intragastric instillation of 200ml tap water with 25g glucose via nasogastric tube
Glucose
25g Glucose in 200ml tap water
Monosodium glutamate preoperative
Single intragastric instillation of 200ml tap water with 1g monosodium glutamate via nasogastric tube
Monosodium glutamate
1g monosodium glutamate in 200ml tap water
Monosodium glutamate postoperative
Single intragastric instillation of 200ml tap water with 1g monosodium glutamate via nasogastric tube
Monosodium glutamate
1g monosodium glutamate in 200ml tap water
Quinine preoperative
Single intragastric instillation of 200ml tap water with 17mg quinine via nasogastric tube
Quinine
17mg quinine in 200ml tap water
Quinine postoperative
Single intragastric instillation of 200ml tap water with 17mg quinine via nasogastric tube
Quinine
17mg quinine in 200ml tap water
Interventions
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Placebo
Tap water 200ml
Glucose
25g Glucose in 200ml tap water
Monosodium glutamate
1g monosodium glutamate in 200ml tap water
Quinine
17mg quinine in 200ml tap water
Eligibility Criteria
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Inclusion Criteria
* right handed
Exclusion Criteria
* neurologic/psychiatric disorders
18 Years
55 Years
ALL
No
Sponsors
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University Hospital, Basel, Switzerland
OTHER
Responsible Party
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Principal Investigators
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Christoph Beglinger, Prof
Role: STUDY_CHAIR
University Basel
Locations
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University Hopital Basel
Basel, , Switzerland
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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fMRI Taste 2
Identifier Type: -
Identifier Source: org_study_id
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