MedDataX Logo

Taste Perception Pre and Post Bariatric Surgery

NCT ID: NCT01536197

Last Updated: 2017-12-18

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

33 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Study Completion Date

2013-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigators wish to study the effects of three forms of bariatric surgery, gastric bypass lap banding, and sleeve gastrectomy. The surgery is not part of the clinical trial. If your insurance does not cover the procedure, then the patient is responsible for payment of the surgical process. The investigators are doing pre and post surgery testing to provide a better understanding of the effect of bariatric surgery-induced weight-loss on taste perception.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Bariatric surgery is the most effective weight loss therapy for obesity. However, the mechanisms responsible for decreased food intake are incompletely understood. One possible mechanism that could account for decreased food intake is changes in taste perception. Therefore, the primary goal of this proposal is to provide a better understanding of the effects of bariatric surgery-induced weight-loss on taste perception.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Morbid Obesity

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

obesity gastric bypass gastric banding sleeve gastrectomy weight loss taste perception

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Gastric Bypass

morbidly obese subjects undergoing gastric bypass surgery

Gastric bypass

Intervention Type PROCEDURE

Roux-en-Y gastric bypass

Gastric banding

morbidly obese subjects undergoing laparoscopic gastric banding surgery

Gastric banding

Intervention Type PROCEDURE

Laparoscopic adjustable gastric banding

Sleeve gastrectomy

morbidly obese subjects undergoing sleeve gastrectomy surgery

Sleeve gastrectomy

Intervention Type PROCEDURE

Sleeve gastrectomy surgery

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Gastric bypass

Roux-en-Y gastric bypass

Intervention Type PROCEDURE

Gastric banding

Laparoscopic adjustable gastric banding

Intervention Type PROCEDURE

Sleeve gastrectomy

Sleeve gastrectomy surgery

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* BMI \>=35 kg/m²
* on stable dose of medication for at least 4 weeks before the pre-surgery studies
* women

Exclusion Criteria

* smokes \> 7 cigarettes per day
* previous malabsorptive or restrictive intestinal surgery
* pregnant or breastfeeding
* recent history of neoplasia (\< 5 years ago)
* have malabsorptive syndromes and inflammatory intestinal disease
* diabetes mellitus
* show signs of oral disease or xerostomia (i.e. dry mouth)
* history of chronic rhinitis
* on medication that might affect taste
* severe organ disfunction
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Washington University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Samuel Klein, M.D.

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Washington University School of Medicine

St Louis, Missouri, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

09-0175B

Identifier Type: -

Identifier Source: org_study_id