The Relationship Between Olfactory and Gustatory Senses, Hedonic Hunger, and Diet Quality After Bariatric Surgery

NCT ID: NCT07290075

Last Updated: 2025-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

101 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2025-01-31

Brief Summary

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This cross-sectional observational study investigates the association between changes in olfactory and gustatory senses and hedonic hunger among individuals who have undergone bariatric surgery. The study also examines the effects of these sensory changes on diet quality and anthropometric measurements. Participants completed a structured questionnaire including sociodemographic and health information, dietary habits, a modified 33-item taste and smell assessment, the Power of Food Scale (PFS), the Mediterranean Diet Adherence Screener (MEDAS), the International Physical Activity Questionnaire (IPAQ), and anthropometric measurements.

Detailed Description

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Obesity is a chronic, multifactorial disease that negatively impacts health and quality of life. Bariatric surgery is an effective treatment option for severe obesity, leading to significant and sustained weight loss as well as improvement in obesity-related comorbidities.

Postoperative changes in taste and smell perception are frequently reported by bariatric patients and may influence food preferences, hedonic hunger, and overall diet quality. These sensory alterations can result from anatomical and hormonal changes after surgery, including altered gut hormone secretion (e.g., PYY, GLP-1, ghrelin) and bile acid metabolism, which affect appetite regulation and reward pathways.

This cross-sectional observational study evaluated adults aged 18-65 years who had undergone sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) at least three months prior to enrollment. Data collection included sociodemographic and health information, dietary habits, a modified 33-item taste and smell questionnaire, the Power of Food Scale (PFS) to assess hedonic hunger, the Mediterranean Diet Adherence Screener (MEDAS), the International Physical Activity Questionnaire (IPAQ), and anthropometric measurements. Nutrient intakes were analyzed according to the Türkiye Nutrition Guide (TÜBER-2022) reference values.

The primary objective was to determine the relationship between postoperative taste/smell changes and hedonic hunger. Secondary objectives included assessing the association between sensory perception and Mediterranean diet adherence, anthropometric parameters, and nutrient adequacy by surgery type. Findings from this study may guide the development of personalized nutritional follow-up protocols to improve long-term outcomes in bariatric patients.

Conditions

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Obesity Taste Disorders Smell Disorder

Keywords

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Hedonic Hunger bariatric surgery outcomes Mediterranean Diet Nutrient Adequacy Power of Food Scale (PFS) Taste and Smell Questionnaire MEDAS

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Sleeve Gastrectomy (SG)

Participants who underwent sleeve gastrectomy at least 3 months prior to enrollment.

Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB)

Intervention Type OTHER

Participants who have undergone sleeve gastrectomy ≥3 months prior to study enrollment; and Participants who have undergone Roux-en-Y gastric bypass ≥3 months prior to study enrollment.

Roux-en-Y Gastric Bypass (RYGB)

Participants who underwent Roux-en-Y gastric bypass at least 3 months prior to enrollment.

Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB)

Intervention Type OTHER

Participants who have undergone sleeve gastrectomy ≥3 months prior to study enrollment; and Participants who have undergone Roux-en-Y gastric bypass ≥3 months prior to study enrollment.

Interventions

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Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB)

Participants who have undergone sleeve gastrectomy ≥3 months prior to study enrollment; and Participants who have undergone Roux-en-Y gastric bypass ≥3 months prior to study enrollment.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18 to 65 years
* History of bariatric surgery (Sleeve Gastrectomy or Roux-en-Y Gastric Bypass)
* At least 3 months post-surgery at the time of study enrollment
* Able and willing to provide informed consent

Exclusion Criteria

* Pregnancy
* History of neurological disorders affecting taste or smell
* Active upper respiratory infection at the time of assessment
* Severe psychiatric disorders that may impair participation
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Uskudar University

OTHER

Sponsor Role collaborator

Hanife Köksal

OTHER

Sponsor Role lead

Responsible Party

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Hanife Köksal

Registered dietitians

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Istanbul University, Faculty of Medicine, Department of Endocrinology and Metabolism

Istanbul, Capa, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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USK-NUTR-HK01

Identifier Type: -

Identifier Source: org_study_id