Pancreatic Cancer Registry: For Any Person With a Personal or Family History

NCT ID: NCT02886247

Last Updated: 2025-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

12000 participants

Study Classification

OBSERVATIONAL

Study Start Date

1994-06-30

Study Completion Date

2032-12-31

Brief Summary

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The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer. The investigators are particularly interested in finding the genes that cause pancreatic cancer to cluster in some families. Up to 10% of pancreatic cancer patients have another close relative who has also developed pancreatic cancer. This clustering of pancreatic cancers in families has yet to be explained; however, the investigators continue to identify new familial pancreatic cancer genes that explain this clustering in subsets of families. For example, in 2009 and 2012 the investigators discovered that mutations in the PALB2 and ATM genes jointly account up to 5% of the clustering of pancreatic cancer in families.

Detailed Description

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Conditions

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Pancreatic Cancer, ATM, BRCA, Hereditary Cancer

Study Design

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Observational Model Type

FAMILY_BASED

Study Time Perspective

PROSPECTIVE

Study Groups

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participants

individuals with a personal or family history of pancreas tumors

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* personal or family history of pancreas tumors

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Johns Hopkins University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alison Klein, PhD, MHS

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins University

Locations

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Johns Hopkins Hospital

Baltimore, Maryland, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Alison Klein, PhD, MHS

Role: CONTACT

410-955-3502

Facility Contacts

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Alison Klein, PhD, MHS

Role: primary

410-955-3511

Role: backup

Other Identifiers

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P50CA062924

Identifier Type: NIH

Identifier Source: secondary_id

View Link

NA_00035453

Identifier Type: -

Identifier Source: org_study_id

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