Pancreas Screening in High Risk Individuals

NCT ID: NCT07012018

Last Updated: 2025-06-10

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 2000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-09-30
• Study Completion Date: 2035-12-31

Brief Summary

Pancreas cancer is the 11th most common cancer in Canada but the 4th most common cause of cancer death because by the time pancreas cancer is detected, it is almost always too advanced for surgery. There are known factors that put individuals at higher risk for pancreas cancer. These include: certain genetic mutations, a family history of pancreas cancer, pancreas cysts and a new diagnosis of diabetes mellitus. Individuals with these risk factors are recommended to undergo pancreas screening with blood tests and yearly imaging tests of the pancreas. Our study will enroll patients with these risk factors and ensure they are managed as per guidelines. Prospectively collected data will include: patient clinicodemographic details, lifestyle factors, screening test results, clinical outcomes and patient reported outcome measures.

Conditions

Pancreas Cancer Screening

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

High risk individuals for pancreas cancer

Individuals undergoing pancreas screening

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Family history of pancreatic cancer, pathogenic variant increasing risk of pancreatic cancer, IPMN, new onset diabetes.

Exclusion Criteria

• Unable to give informed consnet

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of British Columbia

OTHER

Sponsor Role: lead

Responsible Party

Jennifer Telford

Clinical Professor of Medicine

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Jennifer Telford, MD MPH

Role: CONTACT

jtelford@telus.net

1-604-688-6332 ext. 254

Other Identifiers

H25-01796

Identifier Type: -

Identifier Source: org_study_id