Pancreatic Adenocarcinoma Gene Environment Risk Study

NCT ID: NCT00912717

Last Updated: 2025-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-01-31

Study Completion Date

2027-12-31

Brief Summary

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After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Some participants may also be asked to provide a urine sample. Individuals undergoing procedures that require collection of biological samples for clinical purposes may have these samples saved for research purposes. Participants will also be asked for their permission for study investigators to access medical records and/or recontact them for updates to their medical and family histories. Data and biospecimens will be stored for potential future research projects.

Detailed Description

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Conditions

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Pancreatic Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Pancreatic Cancer

individuals who have been diagnosed with pancreatic cancer

No interventions assigned to this group

Unaffected

individuals who have not been diagnosed with pancreatic cancer

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Histologically confirmed or CT confirmed diagnosis of pancreatic adenocarcinoma
* Subjects with abnormal imaging study (CT, MRI, MRCP, EUS)
* Control subjects with a clinical diagnosis of a pancreas, liver, or intestinal condition
* Control subject with acute pancreatitis
* Control subject with chronic pancreatitis
* Control subject with biliary obstruction
* Control subject with pancreatic cyst
* Member of a high risk family (≥ 1 close relative with pancreatic cancer)
* Healthy control (without any of the above conditions)

Exclusion Criteria

* Under the age of 18 years
* Unable to give informed consent
* Inability to travel to Pittsburgh for in-person enrollment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Pittsburgh

OTHER

Sponsor Role lead

Responsible Party

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Randall Brand

M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Randall E Brand, MD

Role: PRINCIPAL_INVESTIGATOR

University of Pittsburgh

Locations

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University of Pittsburgh

Pittsburgh, Pennsylvania, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Randall E Brand, MD

Role: CONTACT

412-623-3105

Beth Dudley, MS, MPH, CGC

Role: CONTACT

412-623-3105

Facility Contacts

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Randall E Brand, MD

Role: primary

412-623-3105

Other Identifiers

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STUDY19070256

Identifier Type: -

Identifier Source: org_study_id

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