Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
80 participants
OBSERVATIONAL
2016-09-27
2019-07-27
Brief Summary
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Detailed Description
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Conditions
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Study Design
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OTHER
PROSPECTIVE
Study Groups
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Obese insulin-resistant subjects
Adipose tissue sampling in obese volunteers (BMI \> 35kg/m2) aged 18- max. 60 years, males and females; insulin-resistant, scheduled for elective bariatric surgery
Adipose tissue sampling
Lean insulin-sensitive controls
Adipose tissue sampling in normal weight patients (BMI \< 27kg/m2) aged 18- max. 60 years, males and females; insulin-sensitive, scheduled for elective surgery
Adipose tissue sampling
Obese diabetic subjects
Adipose tissue sampling in obese volunteers (BMI \> 35kg/m2) aged 18- max. 60 years, males and females; diabetic, scheduled for elective bariatric surgery
Adipose tissue sampling
Interventions
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Adipose tissue sampling
Eligibility Criteria
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Inclusion Criteria
* Normal weight patients (BMI \< 27kg/m2) aged 18- max. 60 years, males and females; insulin-sensitive, scheduled for elective surgery.
Exclusion Criteria
* Chronic inflammatory disease (inflammatory bowel disease, rheumatoid disease, cancer)
* Acute inflammatory disease
* Known renal disease: kidney failure
* Pregnancy:
* history of gastrointestinal surgery with major changes to the gastrointestinal tract (removal of stomach, any GI-bypass)
* Substance abuse, alcohol abuse
* Inability to follow procedures due to psychological disorders, dementia
* insufficient knowledge of project language (German)
18 Years
60 Years
ALL
Yes
Sponsors
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University Hospital, Basel, Switzerland
OTHER
Responsible Party
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Principal Investigators
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Christoph Beglinger, MD
Role: STUDY_CHAIR
St. Claraspital klinische Forschungsabteilung
Other Identifiers
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mTOR
Identifier Type: -
Identifier Source: org_study_id
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