Search for Fragility Indicators Among People Aged 50+ With Chronic HIV Infection

NCT ID: NCT02874118

Last Updated: 2023-04-07

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 510 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2012-09-26
• Study Completion Date: 2023-04-06

Brief Summary

The frailty and frail elderly was defined in 2001 by Fried as a physiological state of heightened vulnerability to external shocks. 5 criteria for classifying the elderly in 3 categories: frail, pre-frail and not frail. The prevalence of frailty in the general population was estimated to be 7%, 10% and 20% for over 65 years and 45% for over 85 years. This concept is explored in some chronic diseases, in order to prevent the loss of autonomy and tailor the treatment. In the carrier population of HIV, a North American retrospective study showed the frailty syndrome manifested as early as 10 years before, than in the general population. Furthermore various studies show in this specific population, increased incidence of diseases linked to age, suggesting an accelerated and premature aging.

objectives: The objective of this study is to determine the prevalence of frailty defined Fried syndrome in a population of subjects aged 50 and over Holders of chronic HIV infection.

Conditions

Frail in HIV Population

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

HIV Patient population over 50 years old

Group Type: EXPERIMENTAL

Fried scale for frailty assessement

Intervention Type: BEHAVIORAL

Interventions

Fried scale for frailty assessement

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Patient with HIV and followed in the southeastern France area

Exclusion Criteria

• In patient HIV infected patient
• HIV patient disabled (spastic)
• HIV infected for less than a year

• Minimum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Ureielle DESALBRES

Role: STUDY_DIRECTOR

Assistance Publique Hôpitaux de Marseille

Nathalie PETIT, MD

Role: STUDY_DIRECTOR

Assistance Publique Hôpitaux de Marseille

Locations

Assistance Publique Hôpitaux de Marseille

Marseille, , France

Countries

France

Other Identifiers

2011-A01679-32

Identifier Type: OTHER

Identifier Source: secondary_id

2011-41

Identifier Type: -

Identifier Source: org_study_id