Prognosis of a First-Ever Stroke in Persons Living With HIV

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

4 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-12-31

Study Completion Date

2016-12-31

Brief Summary

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With aging of the persons living with HIV, cardiovascular diseases now account for substantial mortality and morbidity. Stroke frequency grows exponentially with aging and its incidence doubles every decade over 55 years of age.

The prognosis of ischemic stroke depends mainly on the care in Stroke Units in the acute phase of the disease (thrombolysis/thrombectomy). It is important that HIV patients are referred to these units in the first hours of a stroke and not to their infectious disease units which is a loss of chance.

It would also be important to know whether HIV patients need specific protocols for stroke emergency management.

The study aims to compare the functional prognosis after the first occurrence of an ischemic stroke, in patients admitted to a Stroke Unit, whether they are infected or not infected by HIV.

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Detailed Description

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Conditions

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Cerebrovascular Accident, Acute HIV

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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HIV patients

HIV patients admitted in Stroke units for the first occurence of acute stroke

stroke center referral

Intervention Type OTHER

non HIV patients

non HIV patients admitted in Stroke units for the first occurence of acute stroke

stroke center referral

Intervention Type OTHER

Interventions

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stroke center referral

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients unexposed to HIV: HIV-1 seronegative OR patients exposed to HIV: HIV seropositive for over 6 months with or without antiretroviral treatment. Confirmed by Elisa and Western blot tests
* admitted for ischemic stroke, defined as a sudden cerebrovascular event confirmed by MRI
* at least 18 years of age
* paired with patients unexposed to HIV, admitted for ischemic stroke, same gender and age

Exclusion Criteria

* antecedents of a symptomatic ischemic or hemorrhagic cerebrovascular event
* no social security benefits;
* Absence of signed informed consent for the study
* Patients currently pregnant or breast-feeding

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No