Coronary Artery Disease (CAD) in Patients HIV-infected

NCT ID: NCT04579146

Last Updated: 2022-01-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-07

Study Completion Date

2023-10-31

Brief Summary

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HIV-infected patients with intermediate-high risk have a high prevalence of CAD and a substantial proportion of obstructive CAD. Degree of stenosis is associated with immunoactivation (lymphocyte and monocyte) and microbial translocation

Detailed Description

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Conditions

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HIV Infections

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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HIV-1 patients and treated effectively for more than 12 months

X-ray examination with contrast by a 64-slice CT coronary angiography.

coronary computed tomographic angiographic (CCTA)

Intervention Type OTHER

x-ray examination with contrast by a 64-slice CT coronary angiography.

Interventions

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coronary computed tomographic angiographic (CCTA)

x-ray examination with contrast by a 64-slice CT coronary angiography.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

HIV-infected patients \>= 45 years with 2 or more CV risk factors currently on ART HIV-RNA \< 50 copies \>= 12 months (one blip allowed) Asymptomatic regarding cardiac symptoms (chest pain, syncope, dyspnea) Stable ART for more than 6 months

Exclusion Criteria

* Sign of coronary pathology (chest pain, syncope, dyspnea).
* ATCD of allergy to IV contrast agents
* Chronic inflammatory disease other than HIV
* Subject to a measure for the protection of justice
Minimum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hôpital Européen Marseille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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BENNANI

Marseille, , France

Site Status RECRUITING

Countries

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France

Facility Contacts

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Myriam BENNANI

Role: primary

0413428351

Other Identifiers

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2019-A00219-48

Identifier Type: -

Identifier Source: org_study_id

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