Prognosis of Acute Coronary Syndrome in HIV-infected Patients
NCT ID: NCT00139958
Last Updated: 2010-07-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
300 participants
OBSERVATIONAL
2003-11-30
2010-07-31
Brief Summary
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Detailed Description
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Methods: Prospective cohort study to compare the evolution and prognosis between HIV and non-HIV patients with an ACS.
Duration of the study: Two years for including patients. Three years of follow-up 100 HIV-patients with ACS and 200 non-HIV patients with ACS will be included in the study. All patients will be included in the study from 30 Intensive Care Unit of Cardiology departments in France.
Results: To compare the incidence of total mortality, cardiovascular mortality (myocardial infarction, sudden death, cardiogenic shock, fatal stroke), morbidity (non fatal myocardial infarction, unstable angina, recurrence of ischemia, cardiac failure, non fatal stroke) and revascularization (percutaneous coronary intervention, coronary artery bypass graft surgery) during a 3-year follow-up between HIV and non-HIV patients with ACS. Univariate and multivariate analysis of predictive factors for cardiovascular events will be done.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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1
No interventions assigned to this group
2
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Man or woman HIV-infected for HIV 1 with or without highly active antiretroviral therapy
* Acute coronary syndromes (STEMI, NSTEMI and unstable angina)
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Saint Antoine University Hospital
OTHER
Responsible Party
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Assistance publique Hôpitaux de Paris
Principal Investigators
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Ariel Cohen, MD, PhD
Role: STUDY_CHAIR
Saint Antoine University Hospital
Locations
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Cardiology department
Paris, , France
Countries
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References
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Robert R, Cottin Y, Potard V, Mary-Krause M, Lang S, Teiger E, Collet JP, Chauvet-Droit M, Ederhy S, Soulat-Dufour L, Ancedy Y, Adavane-Scheuble S, Nhan P, Steg PG, Funck-Brentano C, Costagliola D, Cohen A, Boccara F; on behalf the PACS-HIV Investigators. Coronary Angiographic Features and Major Adverse Cardiac or Cerebrovascular Events in People Living With Human Immunodeficiency Virus Presenting With Acute Coronary Syndrome. Circ Cardiovasc Interv. 2022 Jun;15(6):e011945. doi: 10.1161/CIRCINTERVENTIONS.122.011945. Epub 2022 May 10. No abstract available.
Boccara F, Mary-Krause M, Potard V, Teiger E, Lang S, Hammoudi N, Chauvet M, Ederhy S, Dufour-Soulat L, Ancedy Y, Nhan P, Adavane S, Steg PG, Funck-Brentano C, Costagliola D, Cohen A; PACS-HIV (Prognosis of Acute Coronary Syndrome in HIV-Infected Patients) Investigators dagger. HIV Infection and Long-Term Residual Cardiovascular Risk After Acute Coronary Syndrome. J Am Heart Assoc. 2020 Sep;9(17):e017578. doi: 10.1161/JAHA.119.017578. Epub 2020 Aug 26.
Other Identifiers
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PACS
Identifier Type: -
Identifier Source: org_study_id
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