Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
2000 participants
OBSERVATIONAL
2020-05-11
2025-12-31
Brief Summary
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Detailed Description
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Comprehensive non invasive cardiovascular examination
* Anamnesis
* File recherche,Physical examination
* Documentation of the cardiovascular and antiretroviral medical therapy
* Electrocardiogram
* Transthoracic echocardiography (optional)
* Exercise electrocardiogram (optional)
* Exercise Montreal Cognitive Assessment test (optional)
* Exercise the Grooved Pegboard test (optional)
* Blood and stool sample collection (optional)
* Questionnaire to quality of life and health economics
Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Known HIV-infection
* Signed informed consent
Exclusion Criteria
* Unstable hemodynamic status in the three weeks before inclusion
* Pregnancy
18 Years
ALL
No
Sponsors
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University Hospital, Essen
OTHER
Responsible Party
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Stefan Esser M.D.
Prof. M.D. Head of HPSTD Ambulance, University Hospital, Essen, Principal Investigator
Locations
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Universitätsklinikum Essen, Klinik für Dermatologie
Essen, Nordrheinwestfalen, Germany
HIV physician pratice
Duisburg, North Rhine-Westphalia, Germany
Institut für Medizinische Informatik, Biometrie und Epidemiologie
Essen, North Rhine-Westphalia, Germany
University Hospital of Bochum, Department of Dermatology
Bochum, , Germany
HIV Outpatient Department
Dortmund, , Germany
Countries
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Central Contacts
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Facility Contacts
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References
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Kehrmann J, Menzel J, Saeedghalati M, Obeid R, Schulze C, Holzendorf V, Farahpour F, Reinsch N, Klein-Hitpass L, Streeck H, Hoffmann D, Buer J, Esser S; HIV-HEART Study Group. Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart Disease. J Infect Dis. 2019 Jan 9;219(3):497-508. doi: 10.1093/infdis/jiy524.
Reinsch N, Streeck H, Holzendorf V, Schulze C, Neumann T, Brockmeyer NH, Kehrmann J, Schadendorf D, Esser S; HIV HEART Study Group. B-type natriuretic peptides for the prediction of cardiovascular events and mortality in patients living with HIV: Results from the HIV-HEART study. Int J Cardiol. 2019 Apr 15;281:127-132. doi: 10.1016/j.ijcard.2019.01.066. Epub 2019 Jan 23.
Schulz CA, Mavarani L, Reinsch N, Albayrak-Rena S, Potthoff A, Brockmeyer N, Hower M, Erbel R, Jockel KH, Schmidt B, Esser S; HIV HEART Aging Study Group and Heinz Nixdorf Recall Investigative Group. Prediction of future cardiovascular events by Framingham, SCORE and asCVD risk scores is less accurate in HIV-positive individuals from the HIV-HEART Study compared with the general population. HIV Med. 2021 Sep;22(8):732-741. doi: 10.1111/hiv.13124. Epub 2021 May 24.
Mavarani L, Albayrak-Rena S, Potthoff A, Hower M, Dolff S, Sammet S, Maischack F, Schadendorf D, Schmidt B, Esser S; HIV HEART AGING Study. Changes in body mass index, weight, and waist-to-hip ratio over five years in HIV-positive individuals in the HIV Heart Aging Study compared to the general population. Infection. 2023 Aug;51(4):1081-1091. doi: 10.1007/s15010-023-02009-8. Epub 2023 Mar 17.
Mavarani L, Reinsch N, Albayrak-Rena S, Potthoff A, Hower M, Dolff S, Schadendorf D, Jockel KH, Schmidt B, Esser S. The Association of HIV-Specific Risk Factors with Cardiovascular Events in Addition to Traditional Risk Factors in People Living with HIV. AIDS Res Hum Retroviruses. 2024 Apr;40(4):235-245. doi: 10.1089/AID.2023.0055. Epub 2023 Oct 9.
Other Identifiers
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14-5874-BO
Identifier Type: -
Identifier Source: org_study_id
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