Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older
NCT ID: NCT05858034
Last Updated: 2025-09-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
100 participants
INTERVENTIONAL
2023-06-27
2026-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
SUPPORTIVE_CARE
NONE
Study Groups
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Activity Intervention
Customized selection of exercise and other community and online activity options to improve activity.
Customized activity plan
Clients with identified challenges to successful aging (pre-frail or frail on screening) will be invited to develop an individualized activity plan to increase mobility, strength, and stamina. Plans will combine activities to improve strength (resistance training), balance (balance exercises), and stamina, and establish weekly goals. Resistance bands and pedometers will be provided. Progress will be measured by self-reported adherence to the activity plan at week 2, 4, 8, 12 and 24 (assessed by telephone at weeks 2, 4, 8 and in person at week 12 and 24). Depression questionnaire (PHQ-9), fatigue screen, exhaustion questions, and SF-12, a measure of health-related quality of life, will be administered at baseline, week 12 and 24.
Nutrition Intervention
Development of a customized nutrition plan to address nutritional needs.
Customized nutrition plan
Participants with nutritional needs will have the option of meeting with a nutritionist to develop a personalized nutritional plan with a goal of improving diet quality and optimizing caloric intake. Progress will be measured as above.
Interventions
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Customized activity plan
Clients with identified challenges to successful aging (pre-frail or frail on screening) will be invited to develop an individualized activity plan to increase mobility, strength, and stamina. Plans will combine activities to improve strength (resistance training), balance (balance exercises), and stamina, and establish weekly goals. Resistance bands and pedometers will be provided. Progress will be measured by self-reported adherence to the activity plan at week 2, 4, 8, 12 and 24 (assessed by telephone at weeks 2, 4, 8 and in person at week 12 and 24). Depression questionnaire (PHQ-9), fatigue screen, exhaustion questions, and SF-12, a measure of health-related quality of life, will be administered at baseline, week 12 and 24.
Customized nutrition plan
Participants with nutritional needs will have the option of meeting with a nutritionist to develop a personalized nutritional plan with a goal of improving diet quality and optimizing caloric intake. Progress will be measured as above.
Eligibility Criteria
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Inclusion Criteria
* Age ≥50 years
* Followed by the Atrium Health Wake Forest Baptist Infectious Diseases Specialty Clinic (IDSC)
* Eligible for Ryan White Program
* Able to provide informed consent
* Pre-frail or frail by electronic frailty index (eFI)
Exclusion Criteria
* Unable to complete the required assessments or questionnaires
50 Years
ALL
No
Sponsors
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Health Resources and Services Administration (HRSA)
FED
National Institute on Aging (NIA)
NIH
Wake Forest University Health Sciences
OTHER
Responsible Party
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Principal Investigators
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Caryn G Morse, MD, MPH
Role: PRINCIPAL_INVESTIGATOR
Wake Forest University Health Sciences
Locations
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Atrium Health Wake Forest Baptist
Winston-Salem, North Carolina, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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6 H97HA46081-01-01
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
IRB00095309
Identifier Type: -
Identifier Source: org_study_id
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