Use of Mini-fluid Challenge for Fluid Responsiveness Prediction During One-lung Ventilation

NCT ID: NCT02858115

Last Updated: 2016-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2016-08-31

Brief Summary

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During thoracic surgery, an excessive use of fluid results in pulmonary complications. Dynamic fluid responsiveness predictors are not easily usable during one lung ventilation. The investigators hypothesized that the assessment by transesophageal echocardiography (TEE) of subaortic velocity time index (VTI) variation after 100 ml of crystalloid would predict fluid responsiveness in patients receiving one-lung ventilation.

This retrospective, observational, single center study was from January 2014 to December 2015. The investigators included 105 patients requiring one lung ventilation lung resection. The investigators analysed 39 patients presenting an acute circulatory failure. 100 ml of crystalloid was infused over 1-min. After an echocardiographic assessment at 1-min, remaining 400 ml were administered over 14-min Fluid responsiveness was defined as an increase in the VTI above 15% after infusion of 500 ml of crystalloid.

Detailed Description

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Conditions

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Acute Circulatory Failure During One-lung Ventilation Surgery

Study Design

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Study Time Perspective

RETROSPECTIVE

Study Groups

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one lung ventilation lung

patients requiring one lung ventilation lung resection.

Fluid challenge

Intervention Type OTHER

100 ml of crystalloid was infused over 1-min

Trans-oesophageal echography

Intervention Type OTHER

an echocardiographic assessment at 1-min,

Interventions

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Fluid challenge

100 ml of crystalloid was infused over 1-min

Intervention Type OTHER

Trans-oesophageal echography

an echocardiographic assessment at 1-min,

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Lung resection
* Acute circulatory failure
* One-lung ventilation

Exclusion Criteria

* Sinusal rhythm
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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hôpital Nord Assistance Publique Hôpitaux de Marseille

Marseille, , France

Site Status

Countries

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France

Other Identifiers

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2014-30

Identifier Type: -

Identifier Source: org_study_id

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