Electrohaemodynamic Activity in Epileptic Children : Combined Video-EEG and Near-infrared Spectroscopy (NIRS) Analysis

NCT ID: NCT02814331

Last Updated: 2018-08-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

23 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-10-14

Study Completion Date

2015-04-24

Brief Summary

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Evaluate the contribution of multimodal high-resolution EEG-NIRS electrical and local haemodynamic analysis to spatial localization of epileptogenic foci

Detailed Description

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This study is designed to evaluate the contribution of multimodal high-resolution EEG-NIRS electrical and local haemodynamic analysis (HR-EEG, HR-NIRS) to spatial localization of epileptogenic foci in order to perform multimodal mapping and localization of interictal spikes (by HR-EEG source reconstruction) with the clinical prospects of guiding the SEEG electrode implantation strategy prior to surgery in children with drug-refractory partial epilepsy.

Conditions

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Epilepsy

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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symptomatic partial epilepsy

whose brain MRI is abnormal multimodal high-resolution EEG-NIRS

multimodal high-resolution EEG-NIRS

Intervention Type DEVICE

not symptomatic partial epilepsy

whose brain MRI is normal multimodal high-resolution EEG-NIRS

multimodal high-resolution EEG-NIRS

Intervention Type DEVICE

Interventions

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multimodal high-resolution EEG-NIRS

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Children between the ages of 6 and 18 years
* with drug-refractory partial epilepsy, presenting interictal spikes on standard EEG recordings.

Exclusion Criteria

* Children with a serious congenital malformation.
* Refusal from one of the parents or the child.
* Children with generalized epilepsy or diffuse interictal spikes.
* Children with severely impaired general status and vital functions.
* Children with dermatosis of the face or scalp.
* Children under the age of 6 years or adults over the age of 18 years.
Minimum Eligible Age

6 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire, Amiens

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Fabrice WALLOIS, Md, PhD

Role: PRINCIPAL_INVESTIGATOR

CHU Amiens

Locations

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CHU Amiens

Amiens, , France

Site Status

Countries

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France

Other Identifiers

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PHRCN11-DR-WALLOIS

Identifier Type: -

Identifier Source: org_study_id

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