Non-Helium Magnetoencephalography in Pediatric Refractory Epilepsy
NCT ID: NCT07064421
Last Updated: 2025-07-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
100 participants
OBSERVATIONAL
2024-11-05
2027-12-31
Brief Summary
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The main questions this study aims to answer are:
1. How consistent is MEG with SEEG/ECoG in locating the epileptic focus in children with refractory epilepsy?
2. What is the clinical efficacy of MEG in identifying epileptic foci?
Participants will:
1. Be divided into 2 groups: the case group and the control group. Participants in the case group will undergo both MEG and SEEG/ECoG for preoperative assessment, while patients in the control group will undergo only SEEG/ECoG before surgery.
2. Be followed up at 1, 3, 6, and 12 months after surgery to assess seizure control, neurological function, and quality of life.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Case
Participants in the case group will undergo both MEG and SEEG/ECoG for preoperative assessment.
Magnetoencephalography plus Stereo-electroencephalography/Electrocorticography
Use Magnetoencephalography and Stereo-electroencephalography/Electrocorticography in the preoperative assessment of children with drug-resistant epilepsy, particularly in identifying the seizure focus.
Control
Patients in the control group will undergo only SEEG/ECoG before surgery.
Stereo-electroencephalography/Electrocorticography
Use Stereo-electroencephalography/Electrocorticography in the preoperative assessment of children with drug-resistant epilepsy, particularly in identifying the seizure focus.
Interventions
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Magnetoencephalography plus Stereo-electroencephalography/Electrocorticography
Use Magnetoencephalography and Stereo-electroencephalography/Electrocorticography in the preoperative assessment of children with drug-resistant epilepsy, particularly in identifying the seizure focus.
Stereo-electroencephalography/Electrocorticography
Use Stereo-electroencephalography/Electrocorticography in the preoperative assessment of children with drug-resistant epilepsy, particularly in identifying the seizure focus.
Eligibility Criteria
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Inclusion Criteria
2. Clinically diagnosed with refractory epilepsy;
3. Capable of cooperating with magnetoencephalography evaluation and recording.
Exclusion Criteria
2. Patients using drugs that affect central nervous system function;
3. Patients who are not suitable for surgical procedures;
4. Patients with progressive neurological disorders.
3 Years
18 Years
ALL
No
Sponsors
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Beijing X-Magtech Technology Limited
UNKNOWN
Guangzhou Women and Children's Medical Center
OTHER
Responsible Party
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Locations
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Guangzhou Women and Children's medical center
Guangzhou, Guangdong, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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446A01
Identifier Type: -
Identifier Source: org_study_id
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