Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-28

Study Completion Date

2031-02-27

Brief Summary

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The main goal of this project is to study the mechanisms of epileptic activities using intracranial macro and micro electrodes in epileptic patients undergoing pre-surgical investigation.

The recordings will also be used to study physiological mechanisms like sleep and different cognitive functions.

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Detailed Description

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Conditions

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Focal Epilepsy Electrodes, Implanted Cognitive Function Neurophysiology

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Macro-microelectrode implantation

Implantation of macro-micro electrodes of the Adtech Benkhe-Fried type in epileptic patients who are undergoing evaluation with intracranial EEG electrodes

Group Type EXPERIMENTAL

Intracranial macro-microelectrode recording

Intervention Type DEVICE

Additionnally to clinical macroelectrodes, Benkhe-Fried depth macro-microelectrodes will be implanted and recorded during the pre-surgical investigation of epileptic patients

Interventions

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Intracranial macro-microelectrode recording

Additionnally to clinical macroelectrodes, Benkhe-Fried depth macro-microelectrodes will be implanted and recorded during the pre-surgical investigation of epileptic patients

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with focal drug-resistant epilepsy
* Patients who undergo a presurgical evaluation with intracranial electrodes in the videoEEG unit of the Neurology department at the Pitié-Salpêtrière hospital.
* Patients who have been informed and provided written informed consent to take part in the study

Exclusion Criteria

* Contraindication for an intracranial investigation (with macro-electrodes) : intercurrent infectious syndrome, decompensated associated pathology (cardiac, pulmonary, renal, hepatic), patient with increased risk of infection (ex: under immunosuppressive therapy)
* Pregnant or parturient woman
* Breastfeeding woman
* Minor person or legally protected adult (tutelage, legal guardianship, maintenance of justice)

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No