Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy

NCT ID: NCT07014592

Last Updated: 2025-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

5 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-05

Study Completion Date

2026-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this project is to study how the brain reacts to a small electrical signal. Researchers will be using a novel combination of recording electrodes. The researchers will measure the brain response from these electrodes.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Intractable Epilepsy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Medication-intractable epilepsy

Group Type EXPERIMENTAL

stimulating probes and electrodes

Intervention Type DEVICE

Subdural electrodes and/or ball tip probes will be used intraoperatively to provide electrical stimulation to the brain.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

stimulating probes and electrodes

Subdural electrodes and/or ball tip probes will be used intraoperatively to provide electrical stimulation to the brain.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients with medication intractable epilepsy who are recommended to undergo brain surgery to remove a "seizure" focus
* Can provide informed consent for the study and willing to participate

Exclusion Criteria

* Presence of a permanent electronic implant
* Any chronic medical conditions that prevent safe placement of electrodes
Minimum Eligible Age

22 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Michigan

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Matthew S Willsey

Assistant Professor of Neurosurgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Matthew Willsey, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Michigan

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Michigan

Ann Arbor, Michigan, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Ron Ball

Role: CONTACT

734 936-7010

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Ron Ball

Role: primary

734-936-7010

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

HUM00258281

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Electrochemical and Electrophysiological Study
NCT05273970 ENROLLING_BY_INVITATION NA
Localizing Epileptic Networks Using MRI and iEEG
NCT04649008 RECRUITING EARLY_PHASE1
Electrical Neuromodulation for Focal Epilepsy
NCT05844696 UNKNOWN PHASE1/PHASE2