Navigation and Free Recall in Chronically Implanted Humans

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

9 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-05-31

Study Completion Date

2025-05-31

Brief Summary

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This study is designed to identify brain activity associated with good memory in subjects with a chronically implanted RNS® device and to study the effects of therapeutic stimulation for epilepsy on memory. This will be accomplished through analysis of ECoG data collected during memory encoding for short and long-term free recall as well as during navigation tasks.

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Detailed Description

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Conditions

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Epilepsy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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RNS® Neurostimulator

Subjects with pharmaceutically intractable seizures who have been implanted with a RNS® Neurostimulator.

Group Type EXPERIMENTAL

electrical stimulation

Intervention Type OTHER

Stimulation applied will be within parameters commonly used for the treatment of epilepsy during periods of encoding, recall, and memory maintenance .

Interventions

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electrical stimulation

Stimulation applied will be within parameters commonly used for the treatment of epilepsy during periods of encoding, recall, and memory maintenance .

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* able to give informed consent
* 18 years of age or older
* Diagnosis of epilepsy
* Implanted RNS® device and receiving therapeutic stimulation for epilepsy.
* Capable of completing experimental tasks in the judgment of the Principal Investigator