Treatment of Atrophic Acne Scars With Platelet-Rich Plasma and Skin Needling
NCT ID: NCT02798016
Last Updated: 2018-01-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2015-10-31
2017-10-20
Brief Summary
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Detailed Description
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Skin needling is a technique that uses a sterile micro needles to puncture the skin and release growth factors. The combination of skin needling and PRP could enhance the efficacy of both modalities.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Platelet-Rich Plasma alone
The scars will be injected with Platelet-Rich Plasma alone.
Platelet-Rich Plasma
This Platelet-Rich Plasma will be taken from each patient and is going to be used in the treatment of atrophic acne scars
Platelet-Rich Plasma with micro-needling
The scars will be dealt with using micro-needling as well as injecting Platelet-Rich Plasma
Platelet-Rich Plasma
This Platelet-Rich Plasma will be taken from each patient and is going to be used in the treatment of atrophic acne scars
Micro-needling
Micro-needling will be applied on the acne scars in one side of the face.
Interventions
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Platelet-Rich Plasma
This Platelet-Rich Plasma will be taken from each patient and is going to be used in the treatment of atrophic acne scars
Micro-needling
Micro-needling will be applied on the acne scars in one side of the face.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* systemic retinoids intake in the previous 6 months,
* diabetes, pregnancy, history of keloidal scarring; or patients with severe systemic illness or malignancy
* patients on anticoagulant therapy or aspirin or have a coagulation issue,
* patients with hemoglobin less than 10g\\dl or platelet less than 105 micron\\l
* any previous procedures for acne scar within the last 6 months
18 Years
65 Years
ALL
No
Sponsors
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Damascus University
OTHER
Responsible Party
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Principal Investigators
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Faiez Al-Deghlaoui, MD MSc PhD
Role: STUDY_DIRECTOR
Associate Professor of Dermatology and Veneology, Medical School, University of Damascus
Locations
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Department of Dermatology and Venereology
Damascus, Syrian Arab Republic, Syria
Countries
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References
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Layton AM, Henderson CA, Cunliffe WJ. A clinical evaluation of acne scarring and its incidence. Clin Exp Dermatol. 1994 Jul;19(4):303-8. doi: 10.1111/j.1365-2230.1994.tb01200.x.
Cunliffe WJ, Gould DJ. Prevalence of facial acne vulgaris in late adolescence and in adults. Br Med J. 1979 Apr 28;1(6171):1109-10. doi: 10.1136/bmj.1.6171.1109.
Goulden V, Stables GI, Cunliffe WJ. Prevalence of facial acne in adults. J Am Acad Dermatol. 1999 Oct;41(4):577-80.
Sunitha Raja V, Munirathnam Naidu E. Platelet-rich fibrin: evolution of a second-generation platelet concentrate. Indian J Dent Res. 2008 Jan-Mar;19(1):42-6. doi: 10.4103/0970-9290.38931.
Other Identifiers
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UDMS-Dermat-01-2016
Identifier Type: -
Identifier Source: org_study_id
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