Fractional CO2 Laser Combined With PRP Fluid Versus Gel in Treatment of Acne Scars

NCT ID: NCT04580758

Last Updated: 2020-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

EARLY_PHASE1

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-25

Study Completion Date

2021-01-31

Brief Summary

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This study is to test the efficacy of fractional laser combined with either PRP fluid or PRP gel in the treatment of atrophic acne scars

Detailed Description

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The study will include 20 patients, treated with fractional CO2 laser plus PRP fluid on one side of the face and fractional CO2 laser plus PRP gel on the other side.

Choosing which side of the face will be injected with PRP fluid and which side will be injected with PRP gel will be chosen according to a randomization table for each patient.

Conditions

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Atrophic Acne Scar

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Fractional laser with PRP fluid

Fractional CO2 laser then the PRP is injected afterwards

Group Type ACTIVE_COMPARATOR

Fractional laser with PRP fluid or PRP gel

Intervention Type COMBINATION_PRODUCT

20 participants divided into 2 groups of 10 10 participants will do Fractional laser with PRP fluid sessions and 10 participants will do Fractional laser with PRP gel

Fractional laser with PRP gel

Fractional CO2 laser then the PRP gel is injected afterwards

Group Type ACTIVE_COMPARATOR

Fractional laser with PRP fluid or PRP gel

Intervention Type COMBINATION_PRODUCT

20 participants divided into 2 groups of 10 10 participants will do Fractional laser with PRP fluid sessions and 10 participants will do Fractional laser with PRP gel

Interventions

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Fractional laser with PRP fluid or PRP gel

20 participants divided into 2 groups of 10 10 participants will do Fractional laser with PRP fluid sessions and 10 participants will do Fractional laser with PRP gel

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Age above 18
* Both genders
* Skin types III - V
* Willingness and ability to comply with the requirements of the protocol
* Atrophic acne scars

Exclusion Criteria

* Patients with active acne
* Patients with herpes labialis, bacterial infections, other infections such as HBV. HCV or HIV.
* Oral isotretinoin use in the previous 6 months
* Pregnancy
* Tendency to keloid formation
* Patients with severe systemic illness or malignancy
* Patients with connective tissue diseases
* Patients with bleeding tendencies or any other hematological disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yasmine Ahmed Abd El-Maguid El-Hadidy

OTHER

Sponsor Role lead

Responsible Party

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Yasmine Ahmed Abd El-Maguid El-Hadidy

Dermatology Resident

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Kasr Al Ainy Hospital

Giza, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Heba A Abd El Kader, MD

Role: CONTACT

01142479792

Heba I Gawdat

Role: CONTACT

01142479792

Facility Contacts

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Yasmin A El Hadidy, MB BCh

Role: primary

01142479792

Heba A Abd El Kader, MD

Role: backup

Other Identifiers

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Kasr El Aini Hospital

Identifier Type: -

Identifier Source: org_study_id

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