Cochleural Alternating Acoustic Beam Therapy (CAABT) Versus Masking Intervention for Tinnitus
NCT ID: NCT02774122
Last Updated: 2018-01-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
60 participants
INTERVENTIONAL
2016-04-30
2018-10-31
Brief Summary
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Detailed Description
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CAABT was an innovative tinnitus intervention which based on neural science and cochlear plastic research and aimed to reprogram the central auditory system to neutralize the discordant responses of the dysfunctioning cochlea via acoustic beaming stimuli.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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masking therapy
Masking intervention was a standard monophone tinnitus masking therapy.
masking therapy
Masking intervention was a standard monophone tinnitus masking therapy.
CAABT
CAABT was an innovative tinnitus intervention which based on neural science and cochlear plastic research and aimed to reprogram the central auditory system to neutralize the discordant responses of the dysfunctioning cochlea via acoustic beaming stimuli.
CAABT
CAABT was an innovative tinnitus intervention which based on neural science and cochlear plastic research and aimed to reprogram the central auditory system to neutralize the discordant responses of the dysfunctioning cochlea via acoustic beaming stimuli.
Interventions
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CAABT
CAABT was an innovative tinnitus intervention which based on neural science and cochlear plastic research and aimed to reprogram the central auditory system to neutralize the discordant responses of the dysfunctioning cochlea via acoustic beaming stimuli.
masking therapy
Masking intervention was a standard monophone tinnitus masking therapy.
Eligibility Criteria
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Inclusion Criteria
* Ages between 18-80 years
* Tinnitus undergone for more than 6 months
* Hearing loss of the tinnitus ear not affect communication
* The main tinnitus frequency is less than 8 KHz
* Primary tinnitus
Exclusion Criteria
* Hyperacusis
* Patients were accepting any therapy about tinnitus
* Those who have serious mental illness
* Patients who can't fit the audiological examination and tinnitus tests
* Most of the hearing loss in the middle and severe hearing loss of the tinnitus ear
* Any MRI contraindications
18 Years
80 Years
ALL
No
Sponsors
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Beijing Friendship Hospital
OTHER
Responsible Party
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Shu-sheng Gong
director
Principal Investigators
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Gong shu-sheng, MD
Role: STUDY_DIRECTOR
Beijing Friendship Hospital
Locations
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Otorhinolaryngology Head and Neck Surgery department
Beijing, Beijing Municipality, China
Countries
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References
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Cima RF, Maes IH, Joore MA, Scheyen DJ, El Refaie A, Baguley DM, Anteunis LJ, van Breukelen GJ, Vlaeyen JW. Specialised treatment based on cognitive behaviour therapy versus usual care for tinnitus: a randomised controlled trial. Lancet. 2012 May 26;379(9830):1951-9. doi: 10.1016/S0140-6736(12)60469-3.
Liu C, Zhang J, Qi Z, Yue W, Yuan Y, Jiang T, Zhang S, Zhang S. Therapy effect of cochleural alternating acoustic beam therapy versus traditional sound therapy for managing chronic idiopathic tinnitus patients. Sci Rep. 2024 Mar 11;14(1):5900. doi: 10.1038/s41598-024-55866-0.
Wei X, Lv H, Wang Z, Liu C, Ren P, Zhang P, Chen Q, Liu Y, Zhao P, Gong S, Yang Z, Wang Z. Neuroanatomical Alterations in Patients With Tinnitus Before and After Sound Therapy: A Voxel-Based Morphometry Study. Front Neurosci. 2020 Sep 8;14:911. doi: 10.3389/fnins.2020.00911. eCollection 2020.
Liu C, Lv H, Jiang T, Xie J, He L, Wang G, Liu J, Wang Z, Gong S. The Cochleural Alternating Acoustic Beam Therapy (CAABT): A pre-clinical trial. Am J Otolaryngol. 2018 Jul-Aug;39(4):401-409. doi: 10.1016/j.amjoto.2018.04.002. Epub 2018 Apr 3.
Other Identifiers
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961619
Identifier Type: -
Identifier Source: org_study_id
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