Time,Self and Spontaneous Mental Activities in Patients With Psychotic Disorders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-16

Study Completion Date

2025-07-01

Brief Summary

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The main purpose of the study is to examine to which extent abnormalities in the dynamics of neural activities observed in patients with psychosis is related to difficulties at ordering simple visual stimuli and/or personal events.

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Detailed Description

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Conditions

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Schizophrenia Bipolar Disorder

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Healthy volunteer

Group Type EXPERIMENTAL

fMRI

Intervention Type OTHER

Connectivity between the areas related to information processing over time and the areas activated during the rest activity. We will verify whether the activation anomalies observed during time tasks predict anomalies in spontaneous activity dynamics.

EEG

Intervention Type OTHER

link between EEG response anomalies related to information processing over time and response anomalies recorded during rest activity. We will check whether anomalies in EEG oscillatory responses during time tasks predict anomalies during the rest task.

Patients with schizophrenia

Group Type EXPERIMENTAL

fMRI

Intervention Type OTHER

Connectivity between the areas related to information processing over time and the areas activated during the rest activity. We will verify whether the activation anomalies observed during time tasks predict anomalies in spontaneous activity dynamics.

EEG

Intervention Type OTHER

link between EEG response anomalies related to information processing over time and response anomalies recorded during rest activity. We will check whether anomalies in EEG oscillatory responses during time tasks predict anomalies during the rest task.

Patient with bipolar disorder

Group Type EXPERIMENTAL

fMRI

Intervention Type OTHER

Connectivity between the areas related to information processing over time and the areas activated during the rest activity. We will verify whether the activation anomalies observed during time tasks predict anomalies in spontaneous activity dynamics.

EEG

Intervention Type OTHER

link between EEG response anomalies related to information processing over time and response anomalies recorded during rest activity. We will check whether anomalies in EEG oscillatory responses during time tasks predict anomalies during the rest task.

Interventions

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fMRI

Connectivity between the areas related to information processing over time and the areas activated during the rest activity. We will verify whether the activation anomalies observed during time tasks predict anomalies in spontaneous activity dynamics.

Intervention Type OTHER

EEG

link between EEG response anomalies related to information processing over time and response anomalies recorded during rest activity. We will check whether anomalies in EEG oscillatory responses during time tasks predict anomalies during the rest task.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 60 years
* Affiliation to a social security insurance
* Written consent given
* Only for patient : DSM criteria for schizophrenia or bipolar disorder

Exclusion Criteria

* Addiction problem
* Invalidating visual sensory problems
* Neurological history
* Pregnancy or breastfeeding
* Legal safeguard
* Participation in another clinical trial
* Contraindication to MRI

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes