The Swedish Study of Irrigation Fluid Temperature in the Evacuation of Chronic Subdural Hematoma

NCT ID: NCT02757235

Last Updated: 2022-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

588 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-03-31

Study Completion Date

2020-10-20

Brief Summary

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The study will be a multicenter randomised controlled trial of the use of irrigation fluid of body temperature versus irrigation fluid of room temperature during burr hole evacuation of chronic subdural hematoma.

Detailed Description

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Conditions

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Chronic Subdural Hematoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Irrigation fluid of body temperature

During burr hole evacuation of the chronic subdural hematoma the irrigation fluid used will be of body temperature (approximately 37 degrees Celsius)

Group Type ACTIVE_COMPARATOR

Irrigation fluid of body temperature

Intervention Type PROCEDURE

Irrigation fluid of body temperature will be used during burr hole evacuation of chronic subdural hematoma

Irrigation fluid of room temperature

During burr hole evacuation of the chronic subdural hematoma the irrigation fluid used will be of room temperature (approximately 22 degrees Celsius)

Group Type ACTIVE_COMPARATOR

Irrigation fluid of room temperature

Intervention Type PROCEDURE

Irrigation fluid of room temperature will be used during burr hole evacuation of chronic subdural hematoma.

Interventions

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Irrigation fluid of body temperature

Irrigation fluid of body temperature will be used during burr hole evacuation of chronic subdural hematoma

Intervention Type PROCEDURE

Irrigation fluid of room temperature

Irrigation fluid of room temperature will be used during burr hole evacuation of chronic subdural hematoma.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with chronic subdural hematoma requiring burr hole evacuation.
* Patients older than 18 years of age.

Exclusion Criteria

* Chronic subdural hematoma requiring surgical treatment other than burr hole evacuation.
* Chronic subdural hematoma in a patient with an intracranial arachnoidal cyst.
* Chronic subdural hematoma in a patient with a Cerebro Spinal Fluid-shunt.
* Patients who have undergone intracranial surgery before.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Karolinska University Hospital

OTHER

Sponsor Role collaborator

Uppsala University Hospital

OTHER

Sponsor Role collaborator

Sahlgrenska University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Andreas Bartley

MD, neurosurgical resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Asgeir Jakola, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Sahlgrenska University Hospital, Department of neurosurgery

Niklas Marklund, MD, Phd

Role: PRINCIPAL_INVESTIGATOR

Akademiska University Hospital, Department of neurosurgery

Jimmy Sundblom, MD, Phd

Role: PRINCIPAL_INVESTIGATOR

Akademiska University Hospital, Department of neurosurgery

Jiri Bartek, MD

Role: PRINCIPAL_INVESTIGATOR

Karolinska University Hospital, Department of neurosurgery

Andreas Bartley, MD

Role: PRINCIPAL_INVESTIGATOR

Sahlgrenska University Hospital, Department of neurosurgery

Magnus Tisell, MD, PhD

Role: STUDY_DIRECTOR

Sahlgrenska Universtiy Hospital, Department of neurosurgery

Petter Förander, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Karolinska University Hospital, Department of neurosurgery

Locations

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Sahlgrenska Universtity Hospital, Department of neurosurgery, Sweden

Gothenburg, , Sweden

Site Status

Karolinska University Hospital, Department of neurosurgery, Sweden

Solna, , Sweden

Site Status

Uppsala University Hospital, Department of neurosurgery, Sweden

Uppsala, , Sweden

Site Status

Countries

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Sweden

References

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Bartley A, Bartek J Jr, Jakola AS, Sundblom J, Falt M, Forander P, Marklund N, Tisell M. Effect of Irrigation Fluid Temperature on Recurrence in the Evacuation of Chronic Subdural Hematoma: A Randomized Clinical Trial. JAMA Neurol. 2023 Jan 1;80(1):58-63. doi: 10.1001/jamaneurol.2022.4133.

Reference Type DERIVED
PMID: 36409480 (View on PubMed)

Bartley A, Jakola AS, Bartek J Jr, Sundblom J, Forander P, Marklund N, Tisell M. The Swedish study of Irrigation-fluid temperature in the evacuation of Chronic subdural hematoma (SIC!): study protocol for a multicenter randomized controlled trial. Trials. 2017 Oct 11;18(1):471. doi: 10.1186/s13063-017-2194-y.

Reference Type DERIVED
PMID: 29021000 (View on PubMed)

Other Identifiers

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SIC01

Identifier Type: -

Identifier Source: org_study_id

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