Delayed Cerebral Infarction Beyond Endoluminal Spasmolysis and Induced Hypertension

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-12-01

Study Completion Date

2030-12-31

Brief Summary

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An observational study of patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage, employing multimodal neuromonitoring.

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Vasospasm

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Detailed Description

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Conditions

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Subarachnoid Aneurysm Hemorrhage Cerebral Vasospasm After Subarachnoid Hemorrhage

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage

Induced hypertension with norepinephrine

Intervention Type DRUG

Induced hypertension with norepinephrine and/or dobutamine to attain clinically established goals of cerebral perfusion pressure in a stepwise fashion, according to clinical routine.

Endoluminal Spasmolysis

Intervention Type DRUG

Endoluminal spasmolysis of cerebral arteries using i.a. Nimodipine, according to clinical protocol and neurointerventionist discretion.

Interventions

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Induced hypertension with norepinephrine

Induced hypertension with norepinephrine and/or dobutamine to attain clinically established goals of cerebral perfusion pressure in a stepwise fashion, according to clinical routine.

Intervention Type DRUG

Endoluminal Spasmolysis

Endoluminal spasmolysis of cerebral arteries using i.a. Nimodipine, according to clinical protocol and neurointerventionist discretion.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Adults 18 years or older
* Critical care after subarachnoid haemorrhage
* Aneurysm secured by surgical clipping or endovascular procedure
* Suspected, emerging or established severe cerebral vasospasm