Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest

NCT ID: NCT00441753

Last Updated: 2009-02-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-09-30

Brief Summary

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Survivors of a cardiac arrest frequently develop severe postanoxic encephalopathy. Derangements in cerebral blood after return of spontaneous circulation play an important role in the pathogenesis of postanoxic encephalopathy. In the present study we examine the effect of mild therapeutic hypothermia on cerebral blood flow and carbondioxide reactivity in patients after cardiac arrest.

Detailed Description

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Conditions

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Cardiac Arrest Post-Anoxic Encephalopathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* adult patients
* GCS after return of circulation \< 7
* Induced mild hypothermia for 24 hours
* primary rhythm ventricular fibrillation

Exclusion Criteria

* Thrombolysis
* Cardiogenic shock with expected survival \< 24 hrs
* Pregnancy
* No informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Radboud University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Radboud UNiversity Nijmegen Medical Centre

Principal Investigators

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Cornelia Hoedemaekers, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Radboud University Medical Center

Johannes van der Hoeven, MD PhD

Role: STUDY_DIRECTOR

Radboud University Medical Center

Locations

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Radboud University Nijmegen Medical Centre

Nijmegen, , Netherlands

Site Status RECRUITING

Countries

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Netherlands

Central Contacts

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Cornelia Hoedemaekers, MD PhD

Role: CONTACT

00.31.24.3617273

Facility Contacts

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Cornelia Hoedemaekers, MD PhD

Role: primary

00.31.24.3617273

Other Identifiers

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KSCH0601

Identifier Type: -

Identifier Source: org_study_id

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