MRI Perfusion in Adnexal Masses

NCT ID: NCT02694406

Last Updated: 2018-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-07-31

Study Completion Date

2017-12-01

Brief Summary

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As ovarian cancer is characterized by an anarchic neovascularization resulting in a wide number of immature microvessels. These vessels are characterized by a lack of coverage by pericytes and the higher expression of one of the receptors of Vascular Endothelial Growth Factor on both endothelial and epithelial cells of ovarian cystadenocarcinomas. These physio pathogenic characteristics have been demonstrated to be in line with variations of MR perfusion parameters.

Unlike many lesions that occur in other parts of the body, biopsy should not be performed in adnexal masses that demonstrate no evidence of peritoneal disease because it may cause spillage of cystic contents, potentially leading to iatrogenic up-staging of what may have been a malignant tumor that was limited.

Detailed Description

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Conditions

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Complex Adnexal Masses

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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MRI perfusion

contrast-enhanced MR imaging including perfusion weighted imaging (PWI)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* complex adnexal mass
* patient fit for surgery

Exclusion Criteria

* any general contraindication to MRI
* severely ill patients
* those with claustrophobia.
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Mohamed Abbas

Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ahmed Abbas

Assiut, Cairo Governorate, Egypt

Site Status

Ahmed Abbas

Asyut, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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MRI-CAM

Identifier Type: -

Identifier Source: org_study_id

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