Assessment of Mediastinal Masses With Diffusion Weighted MR Imaging

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

24 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-12-01

Study Completion Date

2019-12-30

Brief Summary

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Differentiation between benign and malignant mediastinal tumors as well as characterization and grading of malignancy which is essential for treatment planning as well as for prognosis

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Detailed Description

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Differentiation between benign and malignant mediastinal tumors as well as characterization and grading of malignancy is essential for treatment planning as well as for prognosis .

MRI presents valuable diagnostic information in assessing the mediastinum. In addition, special applications have been developed over recent years diffusion-weighted magnetic resonance imaging is one such technique The advent of echo-planar imaging technique has rendered diffusion weighted imaging of the abdomen and thoracic cavity possible .

Quantitative assessment of the mediastinal mass is possible by calculation of apparent diffusion co-efficient value ,which is related to the proportion of extracellular and intracellular component.

The apparent diffusion co-efficient is inversely correlated with tissue cellularity. It is lower in viable tumor tissue with densely packed diffusion-hindering obstacles than in tissue with less densely packed obstacles such as tumor necrosis and benign tissue .

Conditions

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Mediastinal Tumor

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

CROSS_SECTIONAL

Interventions

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MRI diffusion

using MRI diffusion to differentiate between benign and malignant mediastinal masses

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Any age groups
* diagnosis of mediastinal mass (by Multislice Computed Tomography).

Exclusion Criteria

* chemotherapy radiotherapy.
* thoracic surgery.
* cystic mass .
* mass with large amount of necrosis or calcification.
* contraindication of MRI (e.g. pacemakers , claustrophobia).

Eligible Sex

ALL

Accepts Healthy Volunteers

No