PET-CT in Lymphoma Among the Eldery

NCT ID: NCT07259941

Last Updated: 2025-12-02

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 63 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2026-01-01
• Study Completion Date: 2027-02-01

Brief Summary

This study investigates PET-CT imaging patterns and metabolic parameters in elderly patients (≥60 years) diagnosed with lymphoma, aiming to enhance diagnostic accuracy and prognosis using 18F-FDG PET/CT scans.

Detailed Description

This cross-sectional study involves both retrospective and prospective data collection from elderly lymphoma patients (aged 60 years or older) at the Nuclear Medicine Unit, South Egypt Cancer Institute. It evaluates the PET-CT imaging findings alongside metabolic parameters such as Standardized Uptake Value (SUV), Metabolic Tumor Volume (MTV), and Total Lesion Glycolysis (TLG). The study addresses diagnostic challenges in elderly patients due to atypical presentations and comorbidities and fills the gap of scarce local data in Egypt. Imaging analysis includes visual and semiquantitative assessment of lymphatic and extranodal lesions post-injection of 18F-FDG, assessing tumor metabolic activity to provide prognostic insights. Data analysis uses SPSS with relevant statistical tests to validate findings.

Conditions

PET-CT; Lymphoma; Elderly; Metabolic Parameters

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

• Age ≥ 60 years

Histopathological diagnosis of lymphoma

Exclusion Criteria

• Presence of other concurrent active malignancies

Uncontrolled diabetes mellitus with blood glucose > 200 mg/dL at the time of PET/CT scan

• Minimum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Marwa Mamdouh Ekram

Resident at Nuclear Medicine unit, Radiotherapy and Nuclear Medicine Department, South Egypt Cancer Institute

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

PET-CT Imaging in Lymphoma

Identifier Type: -

Identifier Source: org_study_id