Cluster Headache, Addictions and Vascular Function

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

95 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-06-25

Study Completion Date

2016-06-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Cluster headache (CH) is one of the most painful primitive headaches. Developments in neuroimaging have demonstrated activation of the ipsilateral hypothalamic and orexinergic system, which is similar in patients with addictions. CH has strong links to the vascular system but there is no study measuring endothelial function in CH sufferers.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Study of Hypothalamic Metabolism in Spontaneous Cluster Headache Attacks

NCT00458770

Cluster Headache

TERMINATED NA

Occipital Nerve Stimulation in Medically Intractable Chronic Cluster Headache

NCT01151631

Chronic Cluster Headache

COMPLETED PHASE3

Risk Taking and Decision-making in Cluster Headache Patients

NCT06410872

Cluster Headache

COMPLETED

Variability of the Autonomic Nervous System (ANS) During Cluster Headache (CH).

NCT04439409

Cluster Headache

TERMINATED

Cerebral Metabolism in Patients With Refractory Chronic Cluster Headache Treated by Occipital Nerve Stimulation

NCT02081482

Refractory Chronic Cluster Headache

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Several studies have shown an association between Cluster headache (CH) and smoking. However, no data exists on the link between CH and other addictions, and impact of these addictions on clinical characteristics of the disease. In addition, despite the strong biological link between CH and the vascular system, systematic investigations about vascular functions in CH patients are lacking.

This will be a prospective cohort study of 150 patients with CH, conducted in the Headache Center in Bordeaux, France.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cluster Headache

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patient with Cluster headache

Prospective follow-up of patient with Cluster headache

Neurological clinical examination

Intervention Type OTHER

Diagnostic and description of cluster headache

Psychological clinical examination

Intervention Type OTHER

Scale and questionnaires

Questionnaires

Intervention Type OTHER

Psychopathological and cognitive questionnaires

Blood sample

Intervention Type OTHER

Blood sample for DNA collection

Endothelial function measurement

Intervention Type OTHER

Endothelial function will be measured with a noninvasive Peripheral Arterial Tone (PAT) signal technology using the EndoPAT device

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Neurological clinical examination

Diagnostic and description of cluster headache

Intervention Type OTHER

Psychological clinical examination

Scale and questionnaires

Intervention Type OTHER

Questionnaires

Psychopathological and cognitive questionnaires

Intervention Type OTHER

Blood sample

Blood sample for DNA collection

Intervention Type OTHER

Endothelial function measurement

Endothelial function will be measured with a noninvasive Peripheral Arterial Tone (PAT) signal technology using the EndoPAT device

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Presenting a chronic or episodic cluster headache diagnosed according to the International Classification of Headache Disorders (ICH-D III) criteria, in active or inactive phase.