Study of Hypothalamic Metabolism in Spontaneous Cluster Headache Attacks

NCT ID: NCT00458770

Last Updated: 2014-02-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

1 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-05-31

Study Completion Date

2011-05-31

Brief Summary

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Cluster headache is characterized by unilateral excruciating head pain and autonomic dysfunction. Hypothalamic overactivity was observed in nitrate-induced cluster-headache and in only one case of spontaneous cluster headache 'Sprenger et al, 2004). This prompted the application of hypothalamic deep brain stimulation. The aim of this data is to precise the localisation of the hypothalamic activation.

Detailed Description

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Conditions

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Cluster Headache

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Interventions

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position emission transaxial tomography

cerebral position emission transaxial tomography using 18Fluorodeoxyglucose

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* cluster headache in crisis
* no serious illnesses in progress as cancer, autoimmune disease, liver disease
* patient without chronic psychiatric disease excluding moderate and reactional depression
* no demential disease
* no anxious or depressive disease
* no contraindication to PET scan (pregnancy and breast-feeding)
* social security cover
* written informed consent

Exclusion Criteria

* No effective contraception taken
* unable to realize a decubitus of 15 minutes long
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anne DONNET, PH

Role: PRINCIPAL_INVESTIGATOR

Pôle de Neurosciences Cliniques CHU Timone, 204 rue St Pierre, Marseille 13385 cedex 5 France

Locations

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Pôle de Neurosciences Cliniques CHU Timone

Marseille, , France

Site Status

Countries

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France

Other Identifiers

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2009-A00149-48

Identifier Type: -

Identifier Source: secondary_id

2006/22

Identifier Type: -

Identifier Source: org_study_id

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