Circadian Changes of the Hypothalamic Activity in Patients Suffering From Cluster Headache
NCT ID: NCT04409977
Last Updated: 2020-06-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
60 participants
OBSERVATIONAL
2019-06-26
2020-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Patient group
Patients suffering from cluster headache will be included in this group. When analysing the data, the investigators will distinguish those in the in-bout period from those in the out-bout period. People in this group may participate twice: once in the in-bout and once in the out-bout period.
MRI examination
Patient will be scanned in the MRI twice, once at noon (+/- 1 hour), once at 1 a.m. (+/- 1 hour). The investigators will search for any changes in functional connectivity, particular regarding the connection between the hypothalamus and pain-processing networks.
Control group
Participants not suffering from cluster headache will be included in this group.
MRI examination
Patient will be scanned in the MRI twice, once at noon (+/- 1 hour), once at 1 a.m. (+/- 1 hour). The investigators will search for any changes in functional connectivity, particular regarding the connection between the hypothalamus and pain-processing networks.
Interventions
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MRI examination
Patient will be scanned in the MRI twice, once at noon (+/- 1 hour), once at 1 a.m. (+/- 1 hour). The investigators will search for any changes in functional connectivity, particular regarding the connection between the hypothalamus and pain-processing networks.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* knowledge of the german language suffices to understand the information sheet and consent form
* having read, understood and signed the consent form
Exclusion Criteria
* contraindications for the MRI scan (particularly metal splinters, ferromagnetic devices and implants)
* claustrophobia
* obesity (MRI \> 35 kg/m2)
* shift working (last night shift must date back more than one week)
* jet lag (last travel over more than two time zones must date back more than one week)
18 Years
85 Years
ALL
Yes
Sponsors
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University of Zurich
OTHER
Responsible Party
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Principal Investigators
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Heiko Pohl, MD
Role: PRINCIPAL_INVESTIGATOR
University of Zurich
Locations
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University hospital Zurich
Zurich, Canton of Zurich, Switzerland
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2018-02389
Identifier Type: -
Identifier Source: org_study_id
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