Cluster Headache and SPINK-1 Gene

NCT ID: NCT02585739

Last Updated: 2015-10-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2015-07-31

Brief Summary

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Cluster headache (CH) is a rare, excruciating primary headache disorder. A genetic basis has been suggested by family and twin studies, but the mode of transmission seems to vary and the amount of heritability is unclear.

The number of genetic association studies investigating variants implicated in the pathophysiology of CH is limited. The HCRTR2 1246G \> A and the ADH4 925A \> G polymorphisms have been associated with CH. The former has been confirmed and may affect the hypothalamic hypocretin system. The aim of the present study was to investigate the possible link between SPINK 1 gene and cluster headache.

Detailed Description

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Conditions

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Episodic or Chronic Cluster Headache

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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patient

patient with Cluster headache

Group Type EXPERIMENTAL

blood sample

Intervention Type GENETIC

healthy subject

patient without Cluster headache

Group Type OTHER

blood sample

Intervention Type GENETIC

Interventions

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blood sample

Intervention Type GENETIC

Eligibility Criteria

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Inclusion Criteria

* People aged 18 or over
* Patient consulting in Marseille's or Nice's Pain departments
* Patient agreeing to participate to the research study
* Patient with health insurance

Exclusion Criteria

* People aged under 18
* Patient refusing to participate to the research study
* Patient with deprivation of liberty
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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urielle desalbres

Role: STUDY_DIRECTOR

APHM

Locations

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APHM

Marseille, , France

Site Status

Countries

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France

Other Identifiers

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RC12_3011

Identifier Type: OTHER

Identifier Source: secondary_id

2011-19

Identifier Type: -

Identifier Source: org_study_id

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