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The Role of CGRPand Nociceptin in Migraine

NCT ID: NCT00155129

Last Updated: 2005-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-01-31

Study Completion Date

2005-06-30

Brief Summary

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The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.

Detailed Description

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The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.

Conditions

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Migraine Headache

Keywords

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migraine CGRP nociceptin

Study Design

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Observational Model Type

DEFINED_POPULATION

Study Time Perspective

OTHER

Eligibility Criteria

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Exclusion Criteria

\-
Minimum Eligible Age

3 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Taiwan University Hospital

OTHER

Sponsor Role lead

Principal Investigators

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Pi-Chuan Fan

Role: PRINCIPAL_INVESTIGATOR

Department of Pediatric, NTUH

Locations

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Department of Pediatrics

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Pi-Chuan Fan, MD

Role: CONTACT

Email: [email protected]

Li-Chu Chiou, PhD

Role: CONTACT

Facility Contacts

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Pi-Chuan Fan, MD

Role: primary

Other Identifiers

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9361701099

Identifier Type: -

Identifier Source: secondary_id

9361701099

Identifier Type: -

Identifier Source: org_study_id