Maternal Body Composition Regulates Placental Function

NCT ID: NCT02586714

Last Updated: 2025-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

41 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-07-31

Study Completion Date

2013-12-31

Brief Summary

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This study examined the relationships between maternal body composition, placental function, and fetal nutrition and body composition, and sought to determine the most accurate method of maternal body composition analysis in late pregnancy.

Detailed Description

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This study examined the relationships between maternal body composition, placental function, and fetal nutrition and body composition, and sought to determine the most accurate method of maternal body composition analysis in late pregnancy. This project integrates body composition analysis, nutrition, and metabolic factors to study the impact of maternal body composition and diet on placental function and fetal growth.

Research Project: The proposed enrollment of 41 pregnant women at term (\>37 weeks gestation) was completed in September 2013. The subjects underwent four body composition measurements (bioelectrical impedance, skin-fold thickness, BodPod, and deuterium dilution) and dietary surveys along with a fasting blood draw. The subjects returned 2 weeks postpartum for repeat measurements along with a DEXA scan.

Conditions

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Obesity Pregnancy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Normal weight

No intervention

Intervention Type OTHER

Observation only

Overweight

No intervention

Intervention Type OTHER

Observation only

Obese

No intervention

Intervention Type OTHER

Observation only

Interventions

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No intervention

Observation only

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Healthy pregnant women at term with singleton gestation

Exclusion Criteria

Medical condition requiring daily medication Fetal congenital anomalies Diabetes
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Oregon Health and Science University

OTHER

Sponsor Role collaborator

National Center for Research Resources (NCRR)

NIH

Sponsor Role lead

Responsible Party

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Nicole Marshall

Primary Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Marshall NE, Murphy EJ, King JC, Haas EK, Lim JY, Wiedrick J, Thornburg KL, Purnell JQ. Comparison of multiple methods to measure maternal fat mass in late gestation. Am J Clin Nutr. 2016 Apr;103(4):1055-63. doi: 10.3945/ajcn.115.113464. Epub 2016 Feb 17.

Reference Type DERIVED
PMID: 26888714 (View on PubMed)

Other Identifiers

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2KL2RR024141-06

Identifier Type: NIH

Identifier Source: org_study_id

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