Unravelling the Interplay of Weight Stigma and Pregnancy Outcomes: A Prospective Cohort Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-06-30

Study Completion Date

2028-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this prospective cohort study is to investigate the contribution of stigma and discrimination due to body size to adverse pregnancy outcomes. We also aim to explore the role of psychological and social factors in this relationship. The specific objectives of this study are:

Objective 1: Explore weight stigma as a mediator of the association between BMI ≥30 kg/m2 and adverse pregnancy outcomes.

Objective 2: Explore confounding factors not previously considered such as weight cycling, trauma, eating disorders, and internalised weight bias as mediators in the relationship between obesity and adverse pregnancy outcomes.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Managing Weight in Pregnancy

NCT01770522

Pregnancy Related

COMPLETED

Pregnancy Cohort Study: Pregnancy as a Window to Future Health

NCT06925815

Healthy Pregnant Women Obese Pregnant Women Gestational Diabetes

RECRUITING

The Important Project of Obese Pregnant Women

NCT05160662

Overweight and Obesity

UNKNOWN NA

Lifestyle Intervention Forever: Healthy Weight for Pregnancy and Birth (Pilot Study)

NCT01693666

Pregnancy Obesity Weight Gain +1 more

COMPLETED NA

Development of a Nationally Scalable Model of Group Prenatal Care to Improve Birth Outcomes: "Expect With Me"

NCT02169024

Pregnancy Premature Birth Infant, Low Birth Weight +2 more

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The specific research questions for each objective are:

Objective 1 RQ1.1: Does weight stigma experienced during pregnancy in a healthcare setting reported up to 34 weeks gestation mediate the association between pre-pregnancy obesity (BMI ≥30) and gestational diabetes mellitis (GDM) (primary outcome)?

RQ1.2: Does weight stigma experienced during pregnancy in a healthcare setting reported up to 34 weeks gestation mediate the association between pre-pregnancy obesity (BMI ≥30) and (i) induction of labour; (iv) mode of birth; (ii) gestational hypertension (any); (iii) infant birth weight; and (iv) establishment of breastfeeding by 6 weeks postpartum (secondary outcomes)?

Objective 2:

RQ2.1: Do weight cycling, history of trauma, history of eating disorders, and internalised weight bias explain any of the variance in the mediation relationships described above?

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Weight Stigma Pregnancy Outcomes Overweight and Obesity

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Pregnant between 10-22 weeks' gestation
* Greater or equal than 18 years of age
* Booked to give birth at Adelaide Women's and Children's Hospital or Royal Women's and Children's Brisbane
* Access to the Internet to complete the survey
* Consents to the extraction of hospital electronic medical record data about the woman and relevant to the study.
* Ability to read and understand English