Study of Placental Function in Healthy and Pathological Pregnancies

NCT ID: NCT02321007

Last Updated: 2025-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-30

Study Completion Date

2031-09-30

Brief Summary

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The purpose of this study is to establish a tissue and data repository consisting of samples of human placentas, umbilical cord blood, and maternal blood, collected at the time of delivery. Specimens will be used in cellular, molecular, and functional studies to learn more about changes in placental structure and function, which can result in serious pregnancy complications and determine life-long health by programming the fetus for future metabolic and cardiovascular disease.

Detailed Description

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Conditions

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Pregnancy

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Healthy women delivering at term
* Women with pregnancy complications such as:

* pre-term birth,
* intrauterine growth restriction,
* diabetes, and
* obesity.

Exclusion Criteria

* Women:

* under stress,
* experiencing pain of labor.
* Pregnancies complicated by other pathologies.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Colorado, Denver

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thomas Jansson, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Colorado, Denver

Locations

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University of Colorado Hospital

Aurora, Colorado, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Anita Kramer

Role: CONTACT

303-724-1653

Facility Contacts

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Anita Kramer

Role: primary

303-724-1653

Other Identifiers

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14-1073

Identifier Type: -

Identifier Source: org_study_id

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