Transciptomic Modification Induced by miRNAs in Endometrial Fluid

NCT ID: NCT02554539

Last Updated: 2018-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-07-01

Study Completion Date

2017-07-01

Brief Summary

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The purpose of this study is to understand the mechanism of communication between the uterine environment and the preimplantation human embryo. The investigators are interested in understanding how the in-utero environment during the window of implantation is different in normal weight and overweight/obese women and how this may impact the programming of the developing embryo.

Detailed Description

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Conditions

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MicroRNA in Endometrial Fluid

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Obese

Women, aged 21-45 with BMI \>30

Group Type EXPERIMENTAL

Endometrial fluid aspiration

Intervention Type PROCEDURE

Patient will undergo a biopsy to aspirate endometrial fluid from the uterine cavity

Normal weight

Women, aged 21-45 with BMI \< 25

Group Type EXPERIMENTAL

Endometrial fluid aspiration

Intervention Type PROCEDURE

Patient will undergo a biopsy to aspirate endometrial fluid from the uterine cavity

Interventions

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Endometrial fluid aspiration

Patient will undergo a biopsy to aspirate endometrial fluid from the uterine cavity

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Meet the WHO criteria for normal weight (BMI \< 25) and overweight/obese (BMI \> 25)
* Age 21-45

Exclusion Criteria

* Age \< 21 or \> 45
* Women with history of hysterectomy
Minimum Eligible Age

21 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Stanford University

OTHER

Sponsor Role lead

Responsible Party

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Meera Sridhar Shah

Clinical Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Stanford University

Stanford, California, United States

Site Status

Countries

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United States

Other Identifiers

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34225

Identifier Type: -

Identifier Source: org_study_id

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