Does DNA Sperm Fragmentation Affects Embryo Morphokinetic?

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-02-29

Study Completion Date

2018-02-28

Brief Summary

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The embryokinetics may be a new prognostic factor for choosing the human embryos with the highest implantation potential. In order to identify the factors that may affect the rate of embryo cleavage, there are many studies about morphokinetics and culture medium, oxygen tension, oocyte quality or type of medication used for ovarian stimulation. However there are no published data with respect to the influence of sperm DNA fragmentation in the embryo kinetic.

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Detailed Description

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Conditions

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Blastocyst Time Pronuclear Appearance Pronuclear Fading Embryo Compaction Cleavage Times

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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MACS

Patients with MACS Selection

Group Type EXPERIMENTAL

MACS

Intervention Type OTHER

Interventions

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MACS

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients 36 to 38 years
* Fresh sample semen
* Minimum 6 oocytes
* Semen sample with at least 5 million/ml and at least 30% of progressive motile sperm.

Exclusion Criteria

* Patients younger than 36 or older than 38 years old
* Frozen semen sample
* Less tan 6 oocytes.
* Semen samples with less than 5 million / ml or less than 30% of motile sperm.

Minimum Eligible Age

36 Years

Maximum Eligible Age

38 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No