Postprandial Plasma Amino Acid Concentrations After Dairy Consumption
NCT ID: NCT02546141
Last Updated: 2016-01-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
10 participants
INTERVENTIONAL
2015-10-31
2015-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
SINGLE
Study Groups
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skimmed milk (UHT)
portion size that contains 25 g of protein, oral, single administration
skimmed milk (UHT)
skimmed milk (pasteurized)
portion size that contains 25 g of protein, oral, single administration
skimmed milk (pasteurized)
skimmed yoghurt
portion size that contains 25 g of protein, oral, single administration
skimmed yoghurt
full-fat milk (UHT)
portion size that contains 25 g of protein, oral, single administration
full-fat milk (UHT)
non-homogenized full-fat milk (pasteurized)
portion size that contains 25 g of protein, oral, single administration
non-homogenized full-fat milk (pasteurized)
full-fat cheese (semi-matured)
portion size that contains 25 g of protein, oral, single administration
full-fat cheese (semi-matured)
whey protein
portion size that contains 25 g of protein, oral, single administration
whey protein
micellar casein
portion size that contains 25 g of protein, oral, single administration
micellar casein
Interventions
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skimmed milk (UHT)
skimmed milk (pasteurized)
skimmed yoghurt
full-fat milk (UHT)
non-homogenized full-fat milk (pasteurized)
full-fat cheese (semi-matured)
whey protein
micellar casein
Eligibility Criteria
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Inclusion Criteria
* BMI 21-30 kg/m2
* Non-smoking
* Healthy as assessed by the NIZO lifestyle and health questionnaire
* Regular and normal Dutch eating habits as assessed by the NIZO lifestyle and health questionnaire (3 main meals per day)
* Veins suitable for cannulation (blood sampling)
Exclusion Criteria
* Having a history of medical or surgical events that may significantly affect the study outcome, including: Inflammatory bowel disease, hepatitis, pancreatitis, ulcers, gastrointestinal or rectal bleeding; major gastrointestinal tract surgery such as gastrectomy, gastroenterostomy, or bowel resection; known or suspected gastrointestinal disorders, colon or GI tract cancer
* Use of the following medication: glucose lowering drugs, insulin; medication that may impact gastric emptying (e.g. gastric acid inhibitors or laxatives)
* Diagnosed with diabetes, being treated for high blood glucose or increased fasting blood glucose (\> 7 mmol/l in finger prick blood) as assessed during screening visit
* For men: Hb \<8,5 mmol/l as assessed during screening visit; for women: Hb \<7,5 mmol/l.
* Use of protein supplements
* Mental status that is incompatible with the proper conduct of the study
* A self-reported reported food allergy or sensitivity to dairy ingredients
* A self-reported allergy or sensitivity to acetaminophen
* Alcohol consumption \> 28 units/week and 4/day
* Reported unexplained weight loss or weight gain of \> 3 kg in the month prior to pre-study screening, or intention to lose weight during the study period
* Reported slimming or medically prescribed diet
* Recent blood donation (\<1 month prior to Day 01 of the study)
* Not willing or afraid to give up blood donation during the study
* Personnel of NIZO food research or Wageningen University, department of Human Nutrition, their partner and their first and second degree relatives
* Not having a general practitioner
* Not willing to accept information-transfer concerning participation in the study, or information regarding his health, like laboratory results and eventual adverse events to and from his general practitioner
60 Years
ALL
Yes
Sponsors
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FrieslandCampina
INDUSTRY
NIZO Food Research
OTHER
Responsible Party
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Locations
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NIZO food research
Ede, , Netherlands
Countries
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Other Identifiers
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METC nr 15/18
Identifier Type: OTHER
Identifier Source: secondary_id
NL53912.081.15
Identifier Type: -
Identifier Source: org_study_id
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