Zip® Surgical Skin Closure Device vs. Staples for Skin Closure in Subjects Having Undergone Bilateral Knee Arthroplasty

NCT ID: NCT02460172

Last Updated: 2019-03-05

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-05-31

Study Completion Date

2017-02-15

Brief Summary

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Study designed to compare the Zip Surgical Skin Closure device vs. conventional staples for wound closure following bi lateral knee replacement surgery.

Detailed Description

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Prospective, randomized, within patient control study comparing the use of Zip Surgical Skin Closure device versus conventional staple placement when utilized for surgical wound closure after bi lateral unicompartmental or bi lateral total knee replacement. A total of up to 25 patients will be enrolled and followed for up to 8 weeks post surgery to evaluate wound healing and overall satisfaction of closure method.

Conditions

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Arthroplasty, Knee Replacement Wound Healing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Zip Surgical Skin Closure

Subject will be randomized to receive one knee (right or left) closed with Zip Surgical Skin Closure and the other knee closed with steel staples.

Group Type ACTIVE_COMPARATOR

Zip Surgical Skin Closure

Intervention Type DEVICE

Non invasive, reversible, skin closure device for closure of the skin layer following surgical incisions or laceration repair.

Steel Staples

Subject will be randomized to receive one knee (right or left) closed with steel staples and the other knee closed with Zip Surgical Skin Closure.

Group Type ACTIVE_COMPARATOR

Steel Staples

Intervention Type DEVICE

Skin closure device for the closure of the skin layer following surgical incision

Interventions

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Zip Surgical Skin Closure

Non invasive, reversible, skin closure device for closure of the skin layer following surgical incisions or laceration repair.

Intervention Type DEVICE

Steel Staples

Skin closure device for the closure of the skin layer following surgical incision

Intervention Type DEVICE

Other Intervention Names

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Zip16 Zip 8i Conventional staples

Eligibility Criteria

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Inclusion Criteria

1. Patients 18 years of age and older
2. Patients requiring epidermal closure after bi lateral total or partial (unicompartmental) knee arthroplasty
3. Patients willing to be evaluated at discharge, 2 weeks, and at the 6 to 8 week post op

Exclusion Criteria

1. Known bleeding disorder not caused by medication
2. Known personal or family history of keloid formation or scar hypertrophy
3. Known allergy or hypersensitivity to non-latex skin adhesives
4. Atrophic skin deemed clinically prone to blistering
5. Any skin disorder affecting wound healing
6. Any other condition that in the opinion of the investigator would make a particular patient unsuitable for this study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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ZipLine Medical Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rodney Benner, MD

Role: PRINCIPAL_INVESTIGATOR

Study Center

Locations

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Shelbourne Knee Center

Indianapolis, Indiana, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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006

Identifier Type: -

Identifier Source: org_study_id

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