Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
211 participants
INTERVENTIONAL
2018-12-19
2021-12-31
Brief Summary
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Detailed Description
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before the start of surgery. The primary investigator will open the sealed envelopes provided by the Indus Hospital Research Center's Clinical Research Unit (CRU) that provides the study arm allocation. The envelopes will follow the SNOSE protocol i.e. they will be sequentially numbered, opaque sealed envelopes. Before opening the envelope, the primary investigator will write the patient's medical record number, date and will sign the envelope. The envelope will contain carbon paper which will transfer the data allocation paper inside.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Arm 1
Right knee wound closure by staples and Left Knee wound closure by sutures
Staples versus sutures
Prolene suture: non-absorbable, sterile surgical suture composed of an isotactic crystalline steroisomer of polypropylene, a synthetic linear polyolefin. After completion of the procedure, deep tissues will closed with subcuticular prolene suture. Compared to the absorbable sutures, prolene is known to cause less infection since it is a monofilament material.
Staples: specialized staples used in surgery in place of sutures to close skin wounds. After completion of the procedure, deep tissues were closed with absorbable braided suture, then the skin will be closed by staples.
Arm 2
Right knee wound closure by sutures and Left Knee wound closure by staples
Staples versus sutures
Prolene suture: non-absorbable, sterile surgical suture composed of an isotactic crystalline steroisomer of polypropylene, a synthetic linear polyolefin. After completion of the procedure, deep tissues will closed with subcuticular prolene suture. Compared to the absorbable sutures, prolene is known to cause less infection since it is a monofilament material.
Staples: specialized staples used in surgery in place of sutures to close skin wounds. After completion of the procedure, deep tissues were closed with absorbable braided suture, then the skin will be closed by staples.
Interventions
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Staples versus sutures
Prolene suture: non-absorbable, sterile surgical suture composed of an isotactic crystalline steroisomer of polypropylene, a synthetic linear polyolefin. After completion of the procedure, deep tissues will closed with subcuticular prolene suture. Compared to the absorbable sutures, prolene is known to cause less infection since it is a monofilament material.
Staples: specialized staples used in surgery in place of sutures to close skin wounds. After completion of the procedure, deep tissues were closed with absorbable braided suture, then the skin will be closed by staples.
Eligibility Criteria
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Inclusion Criteria
* Bilateral knee surgeries
* Patients giving informed consent
Exclusion Criteria
* Patients taking steroids (confirmed by history)
* Body mass index \> 30 (increases chances of wound dehiscence)
* Lack of consent
* Pregnant females (confirmed by history)
40 Years
75 Years
ALL
Yes
Sponsors
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Indus Hospital and Health Network
OTHER
Responsible Party
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Locations
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The Indus Hospital
Karachi, Sindh, Pakistan
Countries
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Other Identifiers
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IRD_IRB_2017_06_006
Identifier Type: -
Identifier Source: org_study_id
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