Working Memory Training for Children With Dyslexia

NCT ID: NCT02429739

Last Updated: 2016-04-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-31

Study Completion Date

2016-04-30

Brief Summary

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The main aim of this interventional study is to investigate whether the effects of computerized working memory training improves reading abilities for children, i.e. ages 9 - 16 years, diagnosed with dyslexia.

Detailed Description

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Dyslexia is a specific learning difficulty which mainly affects the development of literacy and language related skills. It is characterized by difficulties with phonological processing, rapid naming, working memory, processing speed and the automatic development of skills that may not match up to an individual's other cognitive abilities. Phonological processing deficit is well established as one of the main causes of dyslexia. Working memory (WM) is today considered to be a cognitive system that strongly relates to a person's ability to think and learn. Over the last decade an increasing body of evidence indicates that WM deficits may cause particular problems for individuals with dyslexia. This is consistent with many of the every day problems reported by dyslexics and those around them. WM deficits are frequent in children with reading deficits. A major question is whether the WM impairment is secondary to phonological core deficit affecting the phonological loop only, or caused by an additional deficit involving central executive. Exploratory findings from fMRI studies indicates that impaired WM processes in dyslexia have a unique neuronal signature which may be associated with central executive processes. However there are conflicting findings and further studies are needed.

The children in the study, all diagnosed with dyslexia, will be divided into two subgroups (16/16 children). They are randomly allocated to either the adaptive training group or the treatment as usual control group after the baseline assessment. Both groups will meet for baseline testing and re-testing 4 weeks after completed training. Those that serve as non-trained controls will be offered to participate in training after completion of the study.

The intervention in this study aim to increase WM of children with dyslexia. We hypothesise that intensive computerized working memory training will improve reading fluency, speed and comprehension for children with dyslexia.

Conditions

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Dyslexia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Working Memory Training

Behavioral: Cogmed RM working memory training. After baseline assessment participants will be randomized to active training or treatment as usual (waiting). The active group will start immediately and will have 6 weeks to perform the 25 training sessions.

Group Type EXPERIMENTAL

Working memory Training

Intervention Type BEHAVIORAL

The child will use the computer program at home under parental supervision for 25 sessions, each lasting 30 - 45 minutes and the family has 6 weeks to complete the training. Each session consist 8 different tasks presented by an animated robot. The tasks all require the child to hold information in working memory and to manipulate the information.

Other name: Cogmed RoboMemo

Passive control group

The control group will receive "treatment as usual" (Ordinary school days, special education if normally received).

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Working memory Training

The child will use the computer program at home under parental supervision for 25 sessions, each lasting 30 - 45 minutes and the family has 6 weeks to complete the training. Each session consist 8 different tasks presented by an animated robot. The tasks all require the child to hold information in working memory and to manipulate the information.

Other name: Cogmed RoboMemo

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Dyslexia

Exclusion Criteria

* Mental retardation (IQ below 70)
Minimum Eligible Age

9 Years

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sorlandet Hospital HF

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gro CC Lohaugen, Phd

Role: PRINCIPAL_INVESTIGATOR

Sorlandet Hospital HF

Locations

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Sorlandet Hospital

Arendal, Aust-Agder, Norway

Site Status

Countries

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Norway

References

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Baddeley A. The episodic buffer: a new component of working memory? Trends Cogn Sci. 2000 Nov 1;4(11):417-423. doi: 10.1016/s1364-6613(00)01538-2.

Reference Type BACKGROUND
PMID: 11058819 (View on PubMed)

Baddeley A. Working memory and language: an overview. J Commun Disord. 2003 May-Jun;36(3):189-208. doi: 10.1016/s0021-9924(03)00019-4.

Reference Type BACKGROUND
PMID: 12742667 (View on PubMed)

Klingberg T. Training and plasticity of working memory. Trends Cogn Sci. 2010 Jul;14(7):317-24. doi: 10.1016/j.tics.2010.05.002. Epub 2010 Jun 16.

Reference Type BACKGROUND
PMID: 20630350 (View on PubMed)

Klingberg, T (2012). Slik lærer hjernen. Oslo: Pax forlag

Reference Type BACKGROUND

Gathercole SE, Alloway TP. Practitioner review: short-term and working memory impairments in neurodevelopmental disorders: diagnosis and remedial support. J Child Psychol Psychiatry. 2006 Jan;47(1):4-15. doi: 10.1111/j.1469-7610.2005.01446.x.

Reference Type RESULT
PMID: 16405635 (View on PubMed)

Beneventi H, Tonnessen FE, Ersland L, Hugdahl K. Executive working memory processes in dyslexia: behavioral and fMRI evidence. Scand J Psychol. 2010 Jun 1;51(3):192-202. doi: 10.1111/j.1467-9450.2010.00808.x. Epub 2010 Mar 15.

Reference Type RESULT
PMID: 20338015 (View on PubMed)

Holmes J, Gathercole SE, Dunning DL. Adaptive training leads to sustained enhancement of poor working memory in children. Dev Sci. 2009 Jul;12(4):F9-15. doi: 10.1111/j.1467-7687.2009.00848.x.

Reference Type RESULT
PMID: 19635074 (View on PubMed)

Cogmed Working Memory Training (2012) Pearson assesment.no

Reference Type RESULT

Hulme, C & Snowling, M.J.(2009) Developmental Disorders and Language Learning and Cognition, Chichester, WS.: Wiley - Blackwell

Reference Type RESULT

Høien, T (2012) LOGOS; Teoribasert diagnostisering av lesevansker, Logometrica

Reference Type RESULT

Ottem, E og Frost, J (2010) Språk 6-16 Screeningtest, Statped, Bredtvet kompetansesenter

Reference Type RESULT

Swanson, H.L. (2006). Working memory and reading disabilities. I Alloway, T. & Gathercole, S (Red), Working Memory and Neurodevelopmental Disorders. (s. 59 - 88 9, Hove (UK): Psychology Press

Reference Type RESULT

Related Links

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http://cogmed.com

Computerized Working Memory Training, RoboMemo

http://logometrica.no

Standardized Norwegian computerized test for reading processes

Other Identifiers

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Sorlandet Hospital 2014/1057

Identifier Type: -

Identifier Source: org_study_id

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