Prediction and Intervention in Developmental Dyslexia

NCT ID: NCT02217696

Last Updated: 2014-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

110 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-07-31

Study Completion Date

2018-07-31

Brief Summary

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The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to support children with problems during reading acquisition.

Detailed Description

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Conditions

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Developmental Dyslexia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Computerized reading training first

Cross-over design: group first receives the intervention

Group Type EXPERIMENTAL

Computerized reading training

Intervention Type OTHER

Waiting Control First

Cross-over design: group first serves as waiting control

Group Type EXPERIMENTAL

Computerized reading training

Intervention Type OTHER

Interventions

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Computerized reading training

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy, native (CH-) German speaking subjects, with an estimated non-verbal intelligence quotient (IQ) \>=80, without neurological and/or psychiatric disorder (except for attention deficit hyperactivity disorder, specific learning disorders, developmental language impairments)
* Additional criteria for subgroups:
* Recruitment of preschoolers (aged 5.5-7.5 years):
* Healthy children with increased risk for developmental dyslexia in their second year at kindergarten
* Recruitment of children in first grade (aged 6.5-8.5years):
* Children showing impairments in learning to read (first/second grade).
* Adults (aged 20-40 years):
* Healthy, normal reading

Exclusion Criteria

* MRI contraindications
* No history of premature delivery and/or maternal reports of severe prenatal, perinatal or postnatal complications.
Minimum Eligible Age

5 Years

Maximum Eligible Age

9 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Silvia Brem, PhD

Role: PRINCIPAL_INVESTIGATOR

University Clinics for Child and Adolescent Psychiatry, University of Zurich

Locations

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University Clinics for Child and Adolescent Psychiatry, University of Zurich

Zurich, , Switzerland

Site Status RECRUITING

Countries

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Switzerland

Central Contacts

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Silvia Brem, PhD

Role: CONTACT

+41 43 499 2760

Other Identifiers

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32003B_141201/1

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

LEXI SNF32003B_141201/1

Identifier Type: -

Identifier Source: org_study_id

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