Comparison of Postoperative Outcome of Hepatectomy for Living Donors According to Three Different Incision

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-03-31

Study Completion Date

2019-07-31

Brief Summary

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Living donor liver transplantation (LDLT) is an important option for patients with end-stage liver disease requiring liver transplantation. When performing LDLT, the safety and well being of donors is of the utmost importance. The conventional incision for donor hepatectomy is a right subcostal incision with a midline extension up to xiphoid. Minimally invasive liver surgery throughout a single 10 cm upper midline incision without laparoscopic assistance has been widely applied and considered to be safe and effective. Recently, laparoscopic and minimally invasive living donor hepatectomy via transverse incision has been suggested to reduce morbidity and the invasiveness of living donor hepatectomy. Although minimally invasive approach has become the surgical method of choice for many transplant centers, little data on comparing the impact of all three different type incision in living liver donors. In our center, the investigators have adopted three different incision according to surgical teams. The investigators undertook this study with the aims of comparing the pain and quality of life of donors according to type of three different incisions and assessing any benefits to the donor due to the smaller midline incision during the early postoperative period.

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Detailed Description

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Conditions

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Healthy Donors for Liver Transplantation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CI (conventional incision)

The living liver donors underwent hepatectomy using right subcostal incision with a midline extension (conventional incision)

hepatectomy conventional incision

Intervention Type PROCEDURE

This study was a single center, nonrandomized, observational comparative analysis of 3 different surgical technique. Three surgical teams operated alternately at our center, and donors undergoing hepatectomy via three different incision

MI (midline incision)

The living liver donors underwent hepatectomy using upper midline incision (10cm) without laparoscopic assistance

hepatectomy midline incision

Intervention Type PROCEDURE

TI (transverse incision)

The living liver donors underwent hepatectomy using transverse incision with laparosocpic assistance

hepatectomy transverse incision

Intervention Type PROCEDURE

Interventions

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hepatectomy conventional incision

This study was a single center, nonrandomized, observational comparative analysis of 3 different surgical technique. Three surgical teams operated alternately at our center, and donors undergoing hepatectomy via three different incision

Intervention Type PROCEDURE

hepatectomy midline incision

Intervention Type PROCEDURE

hepatectomy transverse incision

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* ASA (American Society of Anesthesiologists) physical status I-II,
* adult undergoing hepatectomy for living donors

Exclusion Criteria

* known allergy to any of the drugs used in this study,
* bleeding diathesis,
* neurologic dysfunction (preexisting lower limb neurological deficit),
* recent systemic or local infections,
* history of drug use, or
* under treatment with opioids because of chronic pain

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes